Reward System Dysfunction and the Motoric-Cognitive Risk Syndrome in Older Persons
During aging, many physiological systems spontaneously change independent of the presence of chronic diseases. The reward system is not an exception and its dysfunction generally includes a reduction in dopamine and glutamate activities and the loss of ...
Fulvio Lauretani +7 more
doaj +3 more sources
Inflammatory biomarkers and motoric cognitive risk syndrome: Multicohort survey
Background: Inflammation may play a role in Motoric Cognitive Risk (MCR) syndrome, a pre-dementia syndrome comprised of slow gait and cognitive complaints. Our objective was to examine associations of inflammatory biomarkers with MCR.
Justina L Groeger +14 more
doaj +2 more sources
Motoric Cognitive Risk Syndrome: Predictor of Dementia and Age-Related Negative Outcomes [PDF]
Cognitive disorders represent a leading cause of disability in the aging population, of which dementia has the highest global burden. Early signs of dementia such as slow gait and memory complaints are known to present well before the overt manifestation
Jagadish K. Chhetri +5 more
doaj +3 more sources
Association between physical activity levels and motoric cognitive risk syndrome in Chinese older adults [PDF]
Objective To investigate the cross-sectional and longitudinal associations between physical activity levels (PAL) and motoric cognitive risk (MCR) syndrome in Chinese older adults.
Yiming Han +4 more
doaj +2 more sources
Bridging Pain and Motoric Cognitive Risk Syndrome: Mediating Effect of Handgrip Strength [PDF]
Xiaojiang Zhao,1,* Yongguo Zhu,2,* Laiguo Han,1 Lei Zhang,1 Jun Chen,3 Hong Ding1 1Department of Physical Education and Arts, Bengbu Medical University, Bengbu, 233030, People’s Republic of China; 2Institute of Snow and Ice Sports ...
Zhao X +5 more
doaj +2 more sources
Self-reported motoric cognitive risk syndrome predicts long-term mortality in older adults [PDF]
Objectives: Motoric cognitive risk syndrome (MCR) is a pre-dementia syndrome characterized by slow gait and subjective cognitive decline, increasing the risk of adverse clinical events such as dementia and falls in older adults.
Yiwen Xing +5 more
doaj +2 more sources
ObjectiveSubjective motoric cognitive risk syndrome (MCR-S) is a well-established screening tool that has been validated for objective motoric cognitive risk syndrome (MCR-O) and predicted risk of incident dementia.
Yiyi Chai +7 more
doaj +3 more sources
Association of motoric cognitive risk syndrome with falls in older adults: findings from three longitudinal studies [PDF]
Background Falls pose a significant threat to older adults’ health, affecting one-third of individuals aged over 65 annually and resulting in severe injuries despite numerous screening tools.
Jiachen Li +5 more
doaj +2 more sources
Daily Diary Smartphone Assessment of Subjective Cognitive Concerns in Motoric Cognitive Risk Syndrome: A Pilot Study [PDF]
Background and Aims Motoric cognitive risk syndrome (MCR), a predementia condition that combines slow gait speed and subjective cognitive concerns (SCC), has broad diagnostic accessibility in resource poor settings as it is inexpensive and simple to ...
Caroline O. Nester +8 more
doaj +2 more sources
The Influence of Chronic Diseases on Motoric Cognitive Risk Syndrome Development
Introduction. Motoric cognitive risk (MCR) syndrome is a syndrome characterized by cognitive complaints or mild cognitive impairment (MCI) identified during tests and accompanied by slow gait but without dementia or autonomy decline.
A. V. Turusheva, E. V. Frolova
doaj +1 more source

