Results 81 to 90 of about 2,121 (215)

D‐stroi – a uniaxial load frame for X‐ray diffraction and imaging

open access: yesJournal of Synchrotron Radiation, EarlyView.
A remote miniature load frame for X‐ray diffraction and imaging applications is presented. The load frame has been assessed for mechanical stability and suitability for various synchrotron X‐ray‐based techniques.We present a remotely controlled miniature load frame for in situ tensile deformation of millimetre‐sized metal samples in synchrotron X‐ray ...
Felix Tristan Frankus   +5 more
wiley   +1 more source

The Thermohydrodynamic Analysis of Sliding Bearing High-Speed Motorized Spindle by Rotor Dynamic

open access: yesMATEC Web of Conferences, 2017
This is paper presents thermohydrodynamic characteristics of high speed motorized spindle sliding bearing rotor system. The dynamic characteristic of the oil film bearing is affected by temperature increment, thereby affecting the high-speed spindle ...
Li Songsheng, Shen Yuan, Lu Yuxin
doaj   +1 more source

Targeting Cell Cycle Vulnerabilities in Cancers: Emerging Strategies for Therapeutic Development

open access: yesCancer Science, EarlyView.
Dysregulated cell cycle control often involves alternative compensatory pathways in cancers to maintain its robustness but provide unique targetable vulnerabilities. We overview recent insights on cancer‐specific vulnerabilities across the cell cycle and discuss how these can be used to develop new therapeutic strategies.
Nana Kamakura   +3 more
wiley   +1 more source

高速电主轴动态特性研究

open access: yesJixie chuandong, 2014
The dynamical characteristics of high speed motorized spindle,which are the core components of numerical control machine tools,has a great influence on the machining precision of workpiece.A bearing-rotor dynamical model for high-speed motorized spindle ...
杨钢
doaj  

Design and application on experimental platform for high-speed bearing with grease lubrication

open access: yesAdvances in Mechanical Engineering, 2015
The experimental platform for high-speed grease is an important tool for research and development of high-speed motorized spindle with grease lubrication. In this article, the experimental platform for high-speed grease is designed and manufactured which
He Qiang   +5 more
doaj   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

open access: yesThe FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti   +3 more
wiley   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

open access: yesThe FEBS Journal, EarlyView.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior   +5 more
wiley   +1 more source

Extracellular fluid viscosity influences the mechanics and migration of MDA‐MB‐231 cells in a macromolecule‐dependent manner

open access: yesThe FEBS Journal, EarlyView.
Macromolecule‐dependent increases in extracellular fluid viscosity alter cell phenotype. These distinct macromolecules create different extracellular environments that modulate cell morphology and mechanoprotein expression, migration and invasion capacity, and cellular mechanical properties.
Ian M. Smith   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy