Results 41 to 50 of about 16,158 (249)

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that preces the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Age and sex-selective predation moderate the overall impact of predators [PDF]

, 2014
© 2014 The Authors. Journal of Animal Ecology published by John Wiley & Sons Ltd on behalf of British Ecological Society. Acknowledgements: Thanks to J. Reid, S. Redpath, A.
Davison, Martin, Hoy, Sarah R, Lambin, Xavier, Marquiss, Michael, Millon, Alexandre, Petty, Steve J, Whitfield, D Philip   +6 more
core   +5 more sources

FASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure

Advanced Science, EarlyView.
Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.
Minghui Liu, Maolan Wu, Meng Gao, Yongchao Li, Miao Yuan, Zhangcheng Liao, Zhi Liu, Yizhou Wang, Yu Cui, Jinbo Chen, Cheng He, Zhiyong Chen, Feng Zeng, Hequn Chen, Zewu Zhu   +14 more
wiley   +1 more source

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

Discovery of Antarctic moulting sites in satellite imagery reveals new threat to emperor penguins

Communications Earth & Environment
Moult is a critical period in the life cycle of emperor penguin. Like other stages of their life history they depend upon Antarctic sea-ice as a platform to moult.
P. T. Fretwell
doaj   +1 more source

Optimális éves viselkedési modellek: út a fiziológiától a populációkig? = Optimal annual routines: a path from physiology to populations? [PDF]

, 2009
A pályázat fő célja annak kiderítése volt, hogy a különböző állapotváltozók hogyan befolyásolják az optimális viselkedést, speciálisan a hogyan befolyásolják a fő életmenet események időzítését az éves cikluson belül. E cél elérése érdekében több modellt
Alasdair, I. Houston, Barta, Zoltán, McNamara, John M., Pap, Péter László   +3 more
core  

N-Jettiness Subtractions for $gg\to H$ at Subleading Power [PDF]

, 2017
$N$-jettiness subtractions provide a general approach for performing fully-differential next-to-next-to-leading order (NNLO) calculations. Since they are based on the physical resolution variable $N$-jettiness, $\mathcal{T}_N$, subleading power ...
Moult, Ian, Rothen, Lorena, Stewart, Iain W., Tackmann, Frank J., Zhu, Hua Xing   +4 more
core   +4 more sources

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

Optimális vedlési stratégiák = Optimal moult strategies [PDF]

, 2009
A pályázat fő célja annak kiderítése volt, hogy a különböző állapotváltozók hogyan befolyásolják az optimális viselkedést, speciálisan a hogyan befolyásolják a fő életmenet események időzítését az éves cikluson belül. E cél elérése érdekében több modellt
Alasdair, I. Houston, Barta, Zoltán, Lendvai, Ádám Zoltán, McNamara, John M., Pap, Péter László   +4 more
core  

In‐vitro puncture experiment using alligator teeth tracks the formation of dental microwear and its association with hardness of the diet

The Anatomical Record, EarlyView.
Abstract With the development of dental microwear texture analysis (DMTA), there has been an increasing application of DMTA for dietary estimation in extant and fossil reptiles, including dinosaurs. While numerous feeding experiments exist for herbivorous mammals, knowledge remains limited for carnivorous reptiles. This study aimed to qualitatively and
K. Usami, M. O. Kubo
wiley   +1 more source