Results 91 to 100 of about 23,615 (359)

High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection

open access: yesAdvanced Science, EarlyView.
Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni   +15 more
wiley   +1 more source

Interview with \u3cem\u3eMonsters of the Midway\u3c/em\u3e author Jeff Rasley [PDF]

open access: yes, 2012
Interview with John Warner for Indie BookSpot about the author’s experience writing, publishing, and marketing his ...
Rasley, Jeff, Warner, John
core   +1 more source

Self‐Adaptive Reflectance Film for Passive Temperature Regulation in Diverse Environments

open access: yesAdvanced Science, EarlyView.
The rising demand for space cooling calls for innovative passive thermal systems. Traditional radiative cooling materials lack efficiency and alignment with cooling needs, limiting their energy‐saving. A smart film (PFSF) that integrates radiative cooling, reflectance tuning, and phase transition, offering adaptable temperature control across climates ...
Shuo Yang   +9 more
wiley   +1 more source

Impacts of Climate Change on Mountaineering Routes in the Écrins Massif (Western Alps, France)

open access: yesRevue de Géographie Alpine
Mountaineering is one of the most affected sports activities due to the current climate crisis and the resulting changes in the physical environment of the high mountain areas. Some routes have disappeared while others are no longer accessible in summer (
Mathis Arnaud   +4 more
doaj   +1 more source

Some principles for mountain pass algorithms, and the parallel distance [PDF]

open access: yesarXiv, 2012
The problem of computing saddle points is important in certain problems in numerical partial differential equations and computational chemistry, and is often solved numerically by a minimization problem over a set of mountain passes. We point out that a good global mountain pass algorithm should have good local and global properties.
arxiv  

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao   +17 more
wiley   +1 more source

Destroying the Ethnosphere? How Tourism Has Impacted the Sherpas of Nepal

open access: yes, 2014
Tourism is perhaps the most salient and impactful process of globalization today. As we are increasingly more mobile, traveling with endless comfort and ease, we explore the far reaches of the planet as ambassadors of our own culture and as agents of ...
Ginder, Joshua H.
core  

Human Factors in High-Altitude Mountaineering [PDF]

open access: yes, 2015
We describe the human performance and cognitive challenges of high altitude mountaineering. The physical (environmental) and internal (health) stresses are first described, followed by the motivational factors that lead people to climb. The statistics of
Keller, John W.   +2 more
core   +2 more sources

Manipulating the Light Systemic Signal HY5 Greatly Improve Fruit Quality in Tomato

open access: yesAdvanced Science, EarlyView.
This study establishes that HY5, activated by low‐dose light, acts as a systemic signal to enhance tomato fruit quality by directly promoting carotenoid synthesis and sugar metabolism. These findings demonstrate HY5's mobility from leaves to fruits and its application potential through nighttime LED lighting, offering a practical strategy for crop ...
Jiachun Wang   +7 more
wiley   +1 more source

Le Cervin, sommet mythique et géomorphosite emblématique des Alpes suisses

open access: yesPhysio-Géo, 2020
Matterhorn, with its pyramidal shape, nearly obsessing in Switzerland, is since its conquest in 1865 an emblematic mountain in the history of mountaineering.
Francis Huguet
doaj   +1 more source

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