Results 181 to 190 of about 93,830 (266)

Digital documentation of railway tunnel inspection in Austria

Civil Engineering Design, Volume 7, Issue 1, Page 3-8, March 2025.
Abstract Infrastructure, especially railway tunnels, require continuous inspection to ensure their safety. Furthermore, the detection of damages at an early stage can improve their service life. These tasks represent a major challenge for those involved and the tunnel down time is a disruption in operation.
Matthias J. Rebhan, Stefan S. Grubinger, Andreas Schüppel, Simona Deutinger, Gernot Schwarzenberger   +4 more
wiley   +1 more source

Metagenomic insights into regional gut microbiota variation of invasive Spodoptera frugiperda across the Gaoligong Mountains. [PDF]

BMC Microbiol
Bi JG, Wang YH, Li PK, Liu Q, Zheng X.
europepmc   +1 more source

Talin1 Adhesion Morphology and Colocalization With Tensin3 Are Largely Unaffected by Polyacrylamide Substrate Stiffness

Cytoskeleton, EarlyView.
ABSTRACT Cells sense the stiffness of their extracellular matrix (ECM) and adapt their behavior accordingly. We investigated how ECM stiffness affects the spatial organization of talin1, a key mechanosensitive focal adhesion protein. Using polyacrylamide (PA) hydrogels with tunable stiffnesses (0.2–188 kPa), we analyzed cell morphology, migration ...
Joanna Hajduk, Patrycja Twardawa, Sylwia Bobis‐Wozowicz, Marta Szewczyk, Zenon Rajfur, Zbigniew Baster   +5 more
wiley   +1 more source

Seasonal Phenology and Temporal Niche Differentiation of Dung Beetle Communities in Yak Dung from Alpine Meadows of the Eastern Qilian Mountains. [PDF]

Biology (Basel)
Mao L, Gou Y, Wei S, Zhao H, Shi J, Yu X.   +5 more
europepmc   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

Soil quality assessment based on the TDS and MDS methods in the Qinling mountains of China. [PDF]

PLoS One
Yang W, Yue J, Liu Q, Liang S, Ye Y.
europepmc   +1 more source

Exposure–Response Analysis of Enfortumab Vedotin Plus Pembrolizumab as First‐Line Therapy for Locally Advanced or Metastatic Urothelial Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Enfortumab vedotin is a nectin‐4‐directed antibody–drug conjugate currently approved in combination with pembrolizumab for the first‐line treatment of locally advanced or metastatic urothelial cancer. Here we describe the exposure–response relationship between enfortumab vedotin exposures and efficacy/safety endpoints in patients who received ≥1 dose ...
Vaishali L. Chudasama, Helen Kastrissios, Hossam Kadry, Daping Zhang, Salaheldin Hamed, Srinivasu Poondru, Souvik Bhattacharya, Russ Wada, Amit Garg, Yen Lin Chia   +9 more
wiley   +1 more source

Reductions in Advanced Chronic Liver Disease Among People Who Inject Drugs: The ETHOS Engage Study. [PDF]

Liver Int
Conway A, Valerio H, Payne J, Silk D, Marshall AD, Martinello M, Tillakeratne S, Dharmayani PNA, Milat A, Amin J, Read P, Degenhardt L, Stevens A, Hayllar J, Christmass M, Cock V, Doumany J, Grebely J, Dore GJ, ETHOS Engage Study Group.   +19 more
europepmc   +1 more source

Considerations for the Integration of Clinical Trials and Real‐World Data

Clinical Pharmacology &Therapeutics, EarlyView.
As clinical decision‐making increasingly moves toward individualized and context‐specific treatment recommendations, reliance on any single evidence source, randomized or observational, may be insufficient. Principled integration of randomized controlled trials and real‐world data, grounded in explicit causal frameworks, offers a path toward evidence ...
Sky Qiu, Charles E. Barr, Lauren Dang, Larry Han, Kajsa Kvist, Hana Lee, Andrew Mertens, Nerissa Nance, Lei Nie, Kara Rudolph, Xu Shi, Jens Tarp, Salina P. Waddy, Kenneth Wiley, Andy Wilson, Margot Lisa Jing Yann, Zhiwei Zhang, Tianyue Zhou, Maya Petersen, Mark van der Laan   +19 more
wiley   +1 more source