Results 71 to 80 of about 945,769 (312)

Enablers of and barriers to ART adherence among female sex workers in mid-western Uganda: a qualitative study

open access: yesAIDS Research and Therapy
Introduction Female sex workers (FSWs) in Uganda experience numerous barriers to antiretroviral therapy (ART) adherence. We used the planned behavior theory to help explore the enablers and barriers to ART adherence among FSWs. Understanding the barriers
David Friday Apuulison   +10 more
doaj   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

open access: yesAdvanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang   +21 more
wiley   +1 more source

Comparative Oligo‐FISH Mapping Illuminates Chromosomal Evolution Among Rutaceae Species Diverged Over 50 Million Years

open access: yesAdvanced Science, EarlyView.
Oligonucleotide‐based fluorescence in situ hybridization probes were developed in the model citrus species Citrus maxima. These probes were applied to comparative karyotyping across 14 species in the Rutaceae family. This analysis revealed chromosomal evolution in lineages that diverged from Citrus nearly 52 million years ago.
Li He   +9 more
wiley   +1 more source

Ectoparasites and Other Arthropod Associates of Some Voles and Shrews From the Catskill Mountains of New York [PDF]

open access: yes, 2017
Reported here from the Catskill Mountains of New York are 30 ectoparasites and other associates from 39 smoky shrews, Sorex fumeus, 17 from 11 masked shrews, Sorex cinereus, 11 from eight long-tailed shrews, Sorex dispar, and 31 from 44 rock voles ...
French, Thomas W, Whitaker, John O, Jr.
core   +2 more sources

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

open access: yesAdvanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang   +3 more
wiley   +1 more source

A geographical model for the altitudinal zonation of mire types in the uplands of western Europe: the example of Les Monts du Forez in eastern France [PDF]

open access: yesMires and Peat, 2014
The geographical distribution of mires in the oceanic mountain ranges of western Europe cannot be explained without bringing together a number of physical and human factors.
H. Cubizolle, G. Thebaud
doaj  

Fouilles, sites ou monuments ?

open access: yesLes Nouvelles de l’Archéologie, 2013
In the course of the 19th century, iconographic development is inseparable from the restoring of the French monuments which had suffered during the French Revolution.
Serge Lewuillon
doaj   +1 more source

Unique Geology and Climbing: A Literature Review

open access: yesGeosciences, 2020
Geological and geomorphological heritage (geoheritage) is often found in mountain domains that also provide resources for climbing, mountaineering, bouldering, and canyoning.
Dmitry A. Ruban, Vladimir A. Ermolaev
doaj   +1 more source

The Efficient Water Market of the Northern Colorado Water Conservancy District: Colorado, USA [PDF]

open access: yes, 2011
The case study presented is focused on the use of tradable and rentable water permits designed to maximise the efficiency of the use of water resources in Colorado (USA). The State of Colorado is divided into two distinct regions: the eastern, dry plains
Charles W. Howe
core  

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