Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
The Impact of Foot and Mouth Disease Outbreaks in Taiwan and South Korea on the Red Meat Industries in Canada and the United States [PDF]
In addition to trade liberalization, other factors have contributed to the strong growth of red meat production in Canada since the end of the 1980s. In particular, the outbreaks of foot and mouth disease (FMD) in Taiwan and in South Korea eliminated two
Gagne, Stephan, Charlebois, Pierre
core +1 more source
The possible role and significance of carrier swamp buffalo in the transmission of Foot and Mouth Disease in South East Asia (SEA) [PDF]
, 2011 Foot and Mouth Disease (FMD) is a serious trans-boundary livestock disease and is present in many parts of the world. It can result in devastating economic impacts in affected countries or regions. It is endemic in South East Asia (SEA) including Lao PDR
Verin, Blesilda
core +1 more source
Quantitative analysis of transmission parameters for bluetongue virus serotype 8 in Western Europe in 2006 [PDF]
, 2011 The recent bluetongue virus serotype 8 (BTV-8) epidemic in Western Europe struck hard. Controlling the infection was difficult and a good and safe vaccine was not available until the spring of 2008.
de Koeijer Aline A +18 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Impact assessment of an independent agency for animal health in England [PDF]
, 2013 The applicability of a stochastic model was explored to assess the impact of a new independent agency for animal health in England in terms of the cost of animal disease outbreaks.
Rocks, Sophie A. +3 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Potential risk of regional disease spread in west Africa through cross-border cattle trade [PDF]
, 2013 Transboundary animal movements facilitate the spread of pathogens across large distances. Cross-border cattle trade is of economic and cultural importance in West Africa.
Bassirou Bonfoh +32 more
core +1 more source
Factors related to the mortality risk of severe hand, foot, and mouth diseases (HFMD): a 5-year hospital-based survey in Guangxi, Southern China. [PDF]
BMC Infect Dis, 2023 Peng Y +13 more
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source