Results 281 to 290 of about 10,046,523 (395)

DKK3 Initially Preserves Acinar Integrity Through MEK‐Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan   +20 more
wiley   +1 more source

Foot & mouth disease [PDF]

open access: yesClinical Microbiology and Infection, 2002
openaire   +1 more source

Dry mouth and older people.

open access: yesAustralian dental journal, 2015
W. M. Thomson
semanticscholar   +1 more source

The Pathogenic Roles of Local Vitamin D Metabolism Defect in Valve Inflammation and Calcification

open access: yesAdvanced Science, EarlyView.
This study identifies the valvular interstitial cell populations responsible for valvular calcification induced by hyperphosphatemia and likely aging, uncovers local vitamin D metabolism defect‐induced inflammation as a critical pathogenic factor of calcific aortic valve disease, and highlights active vitamin D and ERK inhibitor as potential preventive
Ruichen Yang   +10 more
wiley   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

open access: yesAdvanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang   +16 more
wiley   +1 more source

A Multicenter Study on Symptomatic Neonatal Herpes Simplex Virus Infection in Korea From 2008 to 2017. [PDF]

open access: yesJ Korean Med Sci
Kim D   +14 more
europepmc   +1 more source

Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis

open access: yesAdvanced Science, EarlyView.
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li   +12 more
wiley   +1 more source

The Systemic Link Between Oral Health and Cardiovascular Disease: Contemporary Evidence, Mechanisms, and Risk Factor Implications. [PDF]

open access: yesDiseases
Bida FC   +9 more
europepmc   +1 more source

Isolation of Enterovirus 71 from Patients with Hand, Foot and Mouth Disease in a Local Epidemic on March 2006, in Miyagi Prefecture, Japan

open access: bronze, 2006
Chizuko Sato   +8 more
openalex   +2 more sources

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