Results 141 to 150 of about 638,828 (336)

Systemic Toxicity of L‐Mimosine in Rabbits: A Non‐Rodent Model for Safety Assessment

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT L‐mimosine is a non‐protein amino acid primarily found in the Mimosoideae subfamily, with high concentrations in Leucaena leucocephala and Mimosa pudica. These plants are widely used in both human and animal nutrition, as well as in phytotherapeutic applications. While the toxic effects of L‐mimosine have been extensively studied in ruminants,
S. M. Ferreira   +6 more
wiley   +1 more source

Microbiological mechanisms of oral mucosal disease: oral-intestinal crosstalk and probiotic therapy. [PDF]

open access: yesFront Oral Health
Zhou Q   +9 more
europepmc   +1 more source

Saliva as a TDM matrix and its application in the model‐informed precision dosing

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu   +9 more
wiley   +1 more source

Accuracy of Cytological Methods in Early Detection of Oral Squamous Cell Carcinoma and Potentially Malignant Disorders: A Systematic Review and Meta-Analysis. [PDF]

open access: yesJ Oral Pathol Med
Tayebi-Hillali H   +8 more
europepmc   +1 more source

A Randomized Crossover Clinical Study to Assess the Effect of Oral Nicotine Pouches Used for Different Durations on Plasma Nicotine Pharmacokinetics in Healthy Oral Pouch Consumers

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Oral nicotine pouches (NPs), although addictive and not risk‐free, have potential application for a tobacco harm reduction approach. This study aims to further characterize their ability to deliver nicotine effectively. This randomized seven‐way crossover PK study in healthy oral pouch consumers evaluated 11 and 20 mg NPs used for 10, 20, and ...
David Azzopardi   +6 more
wiley   +1 more source

Adenomatoid Hyperplasia Requiring Differential Diagnosis From Malignant Neoplasms: A Report of Two Cases. [PDF]

open access: yesCureus
Kimura T   +7 more
europepmc   +1 more source

Clinical and Biochemical Factors Associated With Infliximab Pharmacokinetics in Adult Patients With Inflammatory Bowel Disease

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Many patients with inflammatory bowel disease (IBD) do not adequately respond to infliximab, potentially due to individual differences in pharmacokinetics (PK). This study aimed to identify clinical and biochemical variables associated with infliximab PK.
Ilse A. Pool   +6 more
wiley   +1 more source

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