Results 211 to 220 of about 51,999 (287)
Disease Clearance in Ulcerative Colitis: A Narrative Review
ABSTRACT Ulcerative colitis (UC) is a chronic relapsing disease with significant associated risks such as colectomy, hospitalization, or colorectal cancer. A treat‐to‐target approach that mitigates disease activity and progression from an early stage is needed.
Silvio Danese+6 more
wiley +1 more source
ABSTRACT Background and Aims The long‐term outcomes of enteroscopic balloon dilation for small bowel strictures in patients with Crohn’s disease are not well understood. Although Crohn’s strictures can be classified into web‐like, ulcerated, and spindle‐shaped strictures based on endoscopic findings, the outcomes of enteroscopic balloon dilation ...
Sung Noh Hong+4 more
wiley +1 more source
ABSTRACT Background There is a need to identify peripheral biomarkers reflective of defined disease associated fibroblasts in Ulcerative Colitis (UC), with the aim of enabling clinical development approaches for novel‐stromal‐targeted therapeutics for individuals at risk for fibrostenotic complications.
Swati Venkat+9 more
wiley +1 more source
Dissecting Microscopic Colitis Immunopathophysiology: Insights From Basic Research
ABSTRACT Microscopic colitis is an inflammatory bowel disease (IBD) comprising two clinically undiscernible entities: collagenous colitis and lymphocytic colitis. Collagenous colitis associates with HLA genes and displays a Th1/Tc1–Th17/Tc17 profile with pericryptal myofibroblast activity, water malabsorption and secondary fluid loss due to altered ...
Andreas Münch+1 more
wiley +1 more source
Dynamic shifts in the oral microbiome during radiotherapy [PDF]
Bracke, Marc+4 more
core +1 more source
ABSTRACT Ulcerative colitis is a chronic immune‐mediated inflammatory disease of the colon that causes considerable morbidity and increases the risk of colorectal cancer. Several targeted therapies have been developed for moderate‐to‐severe ulcerative colitis, significantly improving its management.
Massimo C. Fantini+4 more
wiley +1 more source
Abstract Background Dental disease is a painful and highly prevalent condition in companion rabbits. However, the dental disease management techniques currently employed by UK primary‐care veterinarians and potential associated clinical welfare implications are scarcely described.
Maria A. Jackson+4 more
wiley +1 more source
The regulatory effects and applications of TIGIT/CD155 on the tumor microenvironment in HCC
Background The interaction between TIGIT and CD155 compromises immune cell efficacy in tumor targeting, potentially driving hepatocellular carcinoma (HCC) progression through diverse molecular pathways. What Was Done This study investigates the interplay between CD155 and TIGIT in regulating CD8+ T cell function and elucidates its implications in HCC ...
Wenting Li+10 more
wiley +1 more source
We summarize the taxonomic characteristics, capabilities to adhere to and invade host cells, extra‐oral ectopic colonization pathways, and major pathogenic mechanisms of Fusobacterium nucleatum, and explore the regulation of F. nucleatum’s pathogenesis, aiming to provide references and assistance for the development of clinical interventions and future
Zhiwei Guan, Houbao Qi, Qiang Feng
wiley +1 more source