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Delivery of Renin Inhibitor Through Mouth Mucosa [PDF]

Drug Development and Industrial Pharmacy, 1996
AbstractThe aim of this work was to investigate the efficiency of transporting the orally inactive renin inhibitor A-64662 through oral mucosa-floor of mouth, cheek, or gum-using the dog as an animal model. It has been demonstrated that A-64662, can be effectively delivered to the bloodstream through mouth mucosa with various dosage forms.
Ho-Wah Hui, Mou-Ying Fu Lu
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Morphological evaluation of tongue mucosa in burning mouth syndrome

Archives of Oral Biology, 2012
The aim of the present study was to perform a morphological evaluation by immunofluorescence of biomarkers of keratinocyte intercellular adhesion, and of differentiation in the tongue mucosa of burning mouth syndrome patients (BMS), compared with a control group.A prospective blinded evaluation of tongue mucosal specimens processed for light microscopy
A. Sardella, A. Gualerzi, G. Lodi, C. Sforza, A. Carrassi, E. Donetti   +5 more
openaire   +4 more sources

A post-mortem study of the mucosa in the endentulous mouth.

Journal of Dentistry, 1980
This study demonstrates that meaningful quantitative histological examination can be undertaken on post-mortem specimens. Care is required to avoid tissue damage and to minimize autolytic changes. Quantitative results are presented of examination of oral mucosa at two sites in the edentulous mouth.
I.B. Watson, Donald Gordon MacDonald
openaire   +3 more sources

Saliva on the oral mucosa and whole saliva in women diagnosed with burning mouth syndrome.

Oral Diseases, 2018
OBJECTIVE The aim of the study was to examine mucosal saliva and unstimulated (UWS) and stimulated (SWS) whole saliva secretion rates and associated factors, in 56 female patients diagnosed with BMS and age-matched control women.
Shikhar P. Acharya, C. Hägglin, M. Jontell, B. Wenneberg, J. Ekström, A. Carlén   +5 more
semanticscholar   +1 more source

[Mercury concentration in the mouth mucosa of patients with amalgam fillings].

Deutsche Medizinische Wochenschrift, 2008
Mercury concentrations were measured in specimens of oral mucosa taken during oral surgery from 90 patients (53 men, 37 women, mean age 42 +/- 16 years); 30 of the patients had no amalgam fillings.
B. Willershausen-Zönnchen, M. Zimmermann, A. Defregger, P. Schramel, G. Hamm   +4 more
semanticscholar   +1 more source

Healing of rat mouth mucosa after irradiation with CO2, Nd:YAG, and CO2-Nd:YAG combination lasers.

Scandinavian journal of dental research, 1994
The healing process of wounds made by a combination laser was studied in 90 rats. The laser system enabled both separate and combined use of CO2 and Nd:YAG laser irradiations.
M. Luomanen, R. Rauhamaa-Mäkinen, J. Meurman, T. Kosloff, O. Tiitta   +4 more
semanticscholar   +1 more source

[Effects of chronic alcohol drinking on mouth mucosa. A morphometric study].

Laryngo-Rhino-Otologie, 1996
BACKGROUND Chronic alcohol consumption is a major risk factor for oral and pharyngeal cancer. Besides other mechanisms a toxic effect of ethanol and/or its metabolite acetaldehyde on the oral mucosa and a resulting increased cell regeneration seem to ...
I. A. Born, J. Zöller, Hagen Weidauer, Heinz Maier   +3 more
semanticscholar   +1 more source

[Fordyce spots. A little regarded finding in the area of lip pigmentation and mouth mucosa].

Laryngo-Rhino-Otologie, 1995
Sebaceous glands on the vermilion border of the lips and the oral mucosa are common in adults. Only pathologic sebaceous glands visible through the epithelium should be regarded as Fordyce's granules.
A. Dreher, G. Grevers
semanticscholar   +1 more source