Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek +7 more
wiley +1 more source
Epidemiological Profile of Oral Health Conditions in Ecuador: A Retrospective Study From 2016 to 2022. [PDF]
Cecilia Belén Molina Jaramillo CM +4 more
europepmc +1 more source
ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen +5 more
wiley +1 more source
Patient-reported oral adverse events during cancer chemotherapy: longitudinal evaluation using patient-reported outcomes version of the common terminology criteria for adverse events (PRO-CTCAE) and concordance with clinician assessments. [PDF]
Sakai Y +4 more
europepmc +1 more source
Advances in Regulating Strategies and Applications of Ferroelectric Materials
To meet the demand for precise control of performance in nanoelectronic devices, this paper systematically reviews the latest advances in controlling ferroelectric properties through strategies such as external field modulation, low‐dimensional confinement, interface engineering, and topological structure design.
Jianying Ji, Cong Liu, Dan Luo, Zhou Li
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Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille +6 more
wiley +1 more source
The potential of antimicrobial peptides to treat oral infections and cancer. [PDF]
Carvalho de Paula AE +2 more
europepmc +1 more source
The paper is divided into three main sections: a review of the development of spatial transcriptomics technology, its applications in livestock and poultry research, and its future prospects. This article provides an overview of the current state of spatial transcriptomics in animal research, exploring its integration with multiomics technologies as ...
Mingyu Wang +5 more
wiley +1 more source
Prognostic factors for recurrence and malignant transformation after treatment of oral epithelial dysplasia: A mixed cohort study. [PDF]
Moradipour Z +4 more
europepmc +1 more source
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley +1 more source

