Results 201 to 210 of about 50,276 (341)

Efficacy and Safety of ABBV‐154 for the Treatment of Active Rheumatoid Arthritis: A Phase 2b, Randomized, Placebo‐Controlled Trial

Arthritis &Rheumatology, Accepted Article.
Objective Despite availability of biologics and targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) to treat rheumatoid arthritis (RA), many patients do not experience optimized disease control. Glucocorticoids are effective but have safety risks.
Frank Buttgereit, Atul Singhal, Alan Kivitz, Edit Drescher, Yoshinori Taniguchi, Rosalía Martínez Pérez, Jaclyn Anderson, Ronilda D'Cunha, Weihan Zhao, Nicholas DeVogel, Julie Parmentier, Romy Christmann, Dilek Arikan, Howard Amital   +13 more
wiley   +1 more source

Impact of craniofacial skeletal characteristics on temporomandibular joint's articular disc position in temporomandibular disorders. [PDF]

Sci Rep
Osama A, Musa M, Zhang HJ, Zheng CD, Nasih M, Ren YH, Wang S.   +6 more
europepmc   +1 more source

Expert Perspective: Diagnosis and Treatment of Castleman Disease

Arthritis &Rheumatology, EarlyView.
Castleman disease (CD) is a major diagnostic challenge for rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region, whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y. C. Chen, Lu Zhang, David C. Fajgenbaum   +2 more
wiley   +1 more source

Pediatric computed tomography scan and subsequent risk of malignancy: a nationwide population-based cohort study in Korea using National Cancer Institute dosimetry system for computed tomography (NCICT). [PDF]

BMC Med
Han S, Soh J, Nah S, Han K, Jung JH, Park J, Hwang Y, Lee C, Hong JY.   +8 more
europepmc   +1 more source

Plasma atrial natriuretic factor in patients with cirrhosis [PDF]

, 1985
Arendt, Rainer M., Gerbes, Alexander L., Jüngst, Dieter, Paumgartner, Gustav, Ritter, D., Zähringer, J.   +5 more
core  

Pharmacodynamic Effects of Litifilimab in Lupus in the LILAC Phase II Study: Rapid and Sustained Reductions in Type I Interferon‐Associated Gene Expression and Cytokines

Arthritis &Rheumatology, Accepted Article.
Objective The pharmacodynamic effects of litifilimab on type I interferon (IFN) response and correlations with clinical outcomes were investigated in systemic lupus erythematosus (SLE) and cutaneous lupus erythematosus (CLE). Methods Participants from Part A (SLE) or Part B (CLE with/without SLE) of the randomized phase II LILAC trial who received ...
Richard Furie, Victoria P. Werth, Eric Milliman, Kyle Ferber, Roland Brown, Jad Zoghbi, Nathalie Franchimont, Youmna Lahoud, Catherine Barbey   +8 more
wiley   +1 more source

Oral Undifferentiated Pleomorphic Sarcoma: A Novel <i>SPECC1L::TERT</i> Gene Fusion and a Comprehensive Literature Review. [PDF]

Genes (Basel)
Della Mura M, Sorino J, Maiorano E, Cazzato G, Colagrande A, Manfuso A, Caporusso C, Copelli C, Cascardi E.   +8 more
europepmc   +1 more source

Clonal sharing of CD8+ T‐cells links skin and joint inflammation in psoriatic arthritis

Arthritis &Rheumatology, Accepted Article.
Objective Psoriatic arthritis (PsA) is an HLA class I‐associated inflammatory arthritis that develops in up to 30% of people with psoriasis. We tested the hypothesis that skin and joint inflammation in PsA is linked in terms of CD8+ T‐cell phenotype and clonality.
Lucy E. Durham, Frances Humby, Nora Ng, Roman Laddach, Elizabeth H. Gray, Sarah E. Ryan, Kathryn J.A. Steel, Rosie Ross, Giovanni A. M. Povoleri, Rosamond Nuamah, Kathy Fung, Athul Menon Kallayil, Pawan Dhami, Bruce W. Kirkham, Leonie S. Taams   +14 more
wiley   +1 more source

Cancer Symptom Clusters in Children and Adolescents with Cancer Undergoing Chemotherapy: A Systematic Review. [PDF]

Nurs Rep
Lopes-Júnior LC, Grassi J, Freitas MB, Trigo FES, Jardim FA, Nunes KZ, Vasconcelos KA, Lima RAG.   +7 more
europepmc   +1 more source

Comparative Effectiveness of Abatacept versus Adalimumab in Shared Epitope positive and negative Rheumatoid Arthritis patients

Arthritis &Rheumatology, Accepted Article.
Objectives The effect of the shared epitope (SE), and valine at position 11 (Val11) of HLA‐DRB1, on the activation of CD4+ T cells, is expected to be diminished by abatacept, a co‐stimulation blocker. However, published evidence on the value of genetic stratification for abatacept treatment is conflicting.
Chuan Fu Yap, Nisha Nair, Seema D Sharma, John Bowes, Amirah Binti Mohammad Ariff, Ann W Morgan, John D Isaacs, Anthony G Wilson, Kimme L Hyrich, Suzan Verstappen, James Bluett, Andrew P Morris, Anne Barton, Darren Plant, Sebastien Viatte   +14 more
wiley   +1 more source