Results 201 to 210 of about 389,556 (308)

Bifid Mandibular Condyle Seen in a Patient With Posterior Disk Displacement. [PDF]

Clin Case Rep
Iijima Y, Nakayama N, Takahashi T, Yamada M, Hino S, Horie N, Kaneko T.   +6 more
europepmc   +1 more source

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

Cytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook, Edna C. Hardeman, Peter W. Gunning   +2 more
wiley   +1 more source

Solitary fibrous tumor of the oral cavity: a systematic review of the literature and a new clinicopathologic case report. [PDF]

Front Oral Health
Maglitto F, Inchingolo AD, Cocis S, Copelli C, Marinelli G, Calò F, Ciocia C, Rizzo A, Inchingolo F, Palermo A, Severino M, Inchingolo AM, Dipalma G.   +12 more
europepmc   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

A model-based selection of oral cancer patient for passive scattering proton beam therapy. [PDF]

J Radiat Res
Narita Y, Takayama K, Kato T, Komori S, Seto I, Nakasato T, Murakami M.   +6 more
europepmc   +1 more source

Intelligent Automation Improved Efficiency in Pharmacovigilance Safety Signal Assessment

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacovigilance is the science involving the detection, assessment, understanding, and prevention of adverse events associated with drugs, biologics, or medical devices. In pharmacovigilance, information that suggests a new potential causal relationship between an intervention and an adverse event is called a safety signal. Following their detection,
Jeffrey Warner, Luis Henrique De Souza Teodoro, Anaclara Prada Jardim, Claudia Albera   +3 more
wiley   +1 more source

Histopathological diagnosis in geriatric stomatology: a 45-year retrospective study from Brazil. [PDF]

Braz Oral Res
Nero NRDD, Costa ARGF, Nazário WR, Borges MKR, Pereira MC, Palazzo GMT, Santos DO, Costa Júnior GT, Cardoso SV, Silva MJB, Loyola AM, Faria PR.   +11 more
europepmc   +1 more source

Time‐Dependent Bias and Prognostic Confounding in Exposure–Response Analysis of Targeted Therapies: Lessons from Sunitinib in Metastatic Renal Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Exposure–response (E–R) analyses of sunitinib in metastatic renal cell carcinoma (mRCC) have supported concentration‐guided dose escalation. However, such analyses may be biased when exposure metrics incorporate post‐baseline dose modifications, time‐varying apparent clearance, or baseline factors that influence both pharmacokinetics and clinical ...
Han Liu, Lena E. Friberg
wiley   +1 more source

Mapping Australia's hospital care for malignant neoplasms of the lip, oral cavity, and pharynx: An ecological study. [PDF]

Medicine (Baltimore)
Alsaif MI, Rahmah ASB, Naser AY.
europepmc   +1 more source

Toward Fit‐for‐Purpose Data for Drug Assessment in Non‐small Cell Lung Cancer: A Core Dataset

Clinical Pharmacology &Therapeutics, EarlyView.
Considering the high unmet medical need in people with non‐small cell lung cancer (NSCLC), the drug assessment for targeted therapies often rely on small populations and single‐arm trials, challenging the evaluation by regulatory authorities, health technology assessment bodies (HTAb), and clinicians.
Geeske F. Grit, Maaike van Dartel, Laura Rodwell, Hanneke van der Woude, Cornelis Boersma, Peter G. M. Mol, Doranne Hilarius   +6 more
wiley   +1 more source