Nuclei on the move: LINC complex-dependent and -independent mechanisms of nuclear migration in development. [PDF]
Gümüşderelioğlu S +2 more
europepmc +1 more source
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
A General Upper Bound for the Runtime of a Coevolutionary Algorithm on Impartial Combinatorial Games. [PDF]
Benford A, Lehre PK.
europepmc +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Move to Improve: Co-Designing a Hospital-Based Physical Activity Program for Children With Chronic Health Conditions. [PDF]
Sivaramakrishnan H +10 more
europepmc +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Reply to Arnold et al.: More than words? Defining best practices in assessing surrogate understanding. [PDF]
Pecanac KE, Golden BP.
europepmc +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Predicting Sensory Block Level in Caudal Anesthesia Based on Sacral Canal Anatomical Parameters and Height: Development of an Ordinal Logistic Regression Model and Nomogram. [PDF]
Li Z +5 more
europepmc +1 more source

