Results 51 to 60 of about 1,354,346 (298)

Quickly 'learning' to move optimally. [PDF]

, 2011
People take account of the variability in their movements in a near-optimal manner in various visuo-motor tasks. Is knowledge of one's variability needed for such near-optimal performance, or could it arise from responding to one's success in previous ...
Smeets, J.B.J., Brenner, E., Smeets, J.B.J.; id_orcid, Eli Brenner, Jeroen B. J. Smeets, Brenner, E.; id_orcid   +5 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Nuevo activismo en tiempos de imperialismo The new activismin Imperialistic times

Estudos de Sociologia, 2007
Este artículo se propone subrayar la acción de movimientos contrarios al gobierno de Bush. Defiende la idea de que, tras el recrudecimiento de las fuerzas de vigilancia y seguridad, resultante del atentado de 11 de septiembre, apareció una nueva ...
George Yúdice
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A new low profile antenna with improved performance for satellite on-the-move communications [PDF]

, 2009
A novel design solution for a low-profile fullduplex Satellite-On-The-Move Communications hybrid scanned phased array antenna for low elevation angle coverage (down to 10°) is described. The antenna is operated at Ku-Band.
Yuanyuan Jiang, Alistair Sambell, Foti, Steve, Smith, Dave, Stephen J Foti, Sambell, Alistair, Jiang, Yuanyuan, David Smith   +7 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Beta activity in the premotor cortex is increased during stabilized as compared to normal walking

Frontiers in Human Neuroscience, 2015
Walking on two legs is inherently unstable. Still, we humans perform remarkable well at it, mostly without falling. To gain more understanding of the role of the brain in controlling gait stability we measured brain activity using electro-encephalography
Sjoerd M. Bruijn, Jaap H. Van Dieen, Andreas eDaffertshofer   +2 more
doaj   +1 more source