Results 231 to 240 of about 28,224,284 (340)

Moving Block Preliminary Safety Analysis

This deliverable from Task 5.5 will contain the results of preliminary safety and security analysis. This is expected to contain analysis regarding the operation of a railway without trackside train detection, including in failure conditions. This deliverable is expected to contain recommendations regarding the implementation of a Moving Block ...
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Vaccine effectiveness against influenza A in older adults and the effect of chronic conditions: results from the I-MOVE and VEBIS multicentre European hospital case-control studies, 2015/16-2023/24. [PDF]

BMC Med
Rose AMC, Nicolay N, Mazagatos C, Martínez-Baz I, Launay O, De Mot L, Bella A, Lazar M, Machado A, Kuliešė M, Abela S, Vučina VV, van Gageldonk-Lafeber R, Bino S, Dürrwald R, Paradowska-Stankiewicz I, Horváth JK, Duffy R, Husa P, McMenamin J, Pozo F, Howard J, Latorre-Millán M, Castilla J, Nguyen LBL, Dauby N, Riccardo F, Ivanciuc A, Gomez V, Jančorienė L, Xuereb G, Petrović G, Marbus S, Vasili A, Tolksdorf K, Bogusz J, Oroszi B, Domegan L, Součková L, Marsh K, Bacci S, Kissling E, I-MOVE & VEBIS Hospital Network teams.   +42 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Rationale and protocol for the Time to Move Randomized Crossover Trial: morning versus evening time physical activity and CGM-assessed glucose levels in individuals with pregnancy hyperglycemia. [PDF]

Front Clin Diabetes Healthc
Ehrlich SF, Hallenbeck BR, Lewis J, Yousefi F, Miller JI, Zite NB, Fortner KB, Schoutko WW, Crouter SE, Raynor H, Maples JM.   +10 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Implementability of a co-designed programme to increase tailored exercise to reduce falls in older people from culturally and linguistically diverse communities: protocol for a pilot randomised controlled trial. [PDF]

BMJ Open
Said CM, Ramage ER, Sharma H, Batchelor F, Bicknell E, Bongiovanni L, Brijnath B, Cahill P, Callisaya M, Celestino S, Chudecka A, Engel L, Lim WK, McDonald CE, Pinheiro M, Sherrington C, Vogrin S, Zanker J, Zheng C, Klaic M, MOVE Together: Reduce Falls Collaboration.   +20 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Investigating the long-term impact of a programme of mindfulness combined with exercise delivered online (MOVE) on individuals living with chronic pain-an exploratory one-year follow-up of a feasibility randomised control trial. [PDF]

PLoS One
Deegan O, Yoshitani M, Fullen B, Gordon M, McDonagh O, Sheerin O, Murphy J, Oyebode O, Segurado R, Hearty C, Casey MB, Doody C.   +11 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source