Results 71 to 80 of about 4,260,963 (301)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Genre practices in mechanical engineering academic articles

open access: yesIbérica, 2020
Since move analysis was proposed by Swales (1990), numerous studies have adopted this method to explore organisational patterns in different sections of research articles in a range of disciplines.
Thi Ngoc Phuong Le, Minh Man PhaM
doaj  

A Logic for Strategy Updates

open access: yes, 2011
Notion of strategy in game theory is static and presumably constructed before the game play. The static, pre-determined notion of strategies falls short analyzing perfect information games.
Baskent, Can
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Does Implementing a Research-Based School Counseling Curriculum Enhance Student Achievement? [PDF]

open access: yes, 2004
Carey presents a brief overview and analysis of the article, Helping students improve academic achievement and school success behavior, originally published in Professional School Counseling.
Carey, Jay
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Nietzsche's Critique of Truth [PDF]

open access: yes, 1992
Nietzsche has made many paradoxical remarks about truth, including the claim that truth does not exist. Philosophers have attempted to tease out various theories of truth from his scattered remarks.
Gemes, Ken
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Move Structure of Research Article Abstracts on Management: Contrastive Study (the Case of English and Russian)

open access: yesJournal of Language and Education, 2017
Although a plethora of papers have proved a seminal role of move-based genre analysis in cross-linguistic research of academic communication and EAP/ESP teaching and learning, there is a lack of respective linguistic or pedagogically motivated studies of
Elena Zanina
doaj   +1 more source

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