Results 111 to 120 of about 8,270,084 (301)
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Rhetorical Move Structure in Corporate Annual Reports: Comparing Saudi and American Move Structures
Journal of Contemporary Language ResearchIntroduction: This study applied genre analysis to Saudi and American corporate annual report introductions to examine rhetorical moves, communicative purposes, and discourse structures across banking, energy, and digital sectors. Therefore, the current paper aimed to establish a model for rhetorical moves structure for the corporate introduction ...
openaire +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Research in English Language PedagogyLiterature in the area of generic corpus-based discourse analysis indicates that the characteristics of the literature review part-genre have not been sufficiently scrutinized to decipher its distinctive rhetorical features.
Azadeh Karam Pourchangi +2 more
doaj
Navigating across disciplines in migration and mobility research : a practical and reflective account [PDF]
This working paper draws on the experiences of three scholars involved in the research project “Evolving (Im)Mobility Regimes: Migrant Workers’ Entitlement and Precarization in Times of Crisis”, conducted within the framework of the ‘nccr-on the move ...
Łysienia, Maja +2 more
core +1 more source