Results 141 to 150 of about 7,922,717 (296)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

01496 MOVE Service Trip

Student looking over the cliff's edge.

core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Bounding the Average Move Structure Query for Faster and Smaller RLBWT Permutations. [PDF]

Lebniz Int Proc Inform
Brown NK, Langmead B.
europepmc   +1 more source

01559 MOVE Service Trip

Students posing in front of the David Geffen Building on a MOVE service ...

core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Movi Color: fast and accurate taxonomic classification with the move structure. [PDF]

ACM BCB
Tan S, Majidian S, Langmead B, Zakeri M.
europepmc   +1 more source

01568 MOVE Service Trip

MOVE volunteers working on a house during a service ...

core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Using Systemic Functional Linguistics in the Clinical Management of Neurogenic Communication Disorders: An Introduction and Worked Example. [PDF]

Int J Lang Commun Disord
Archer B, Leaman MC, Husak RS, Akers C, Groenewold R, Keegan L, Mok Z, Spencer L, Gulick E.   +8 more
europepmc   +1 more source