Results 91 to 100 of about 4,488,461 (298)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

You Move Me [PDF]

open access: yes, 2018
You Move Me is an audio-visual installation made by three artists of different disciplines in collaboration with the people in two different European towns; Žagarė, Lithuania, and Northampton, UK.
Riggs, Gemma
core   +4 more sources

Rhetorical Moves and Linguistic Realisations of Economics Research Article Abstracts in International and Vietnam-Based Journals

open access: yesSAGE Open
Despite the existing scholarship on the contrastive genre-based studies of research abstracts across contexts and cultures, this strand of research is underexplored in Vietnam.
Minh Hieu Nguyen
doaj   +1 more source

Navigating across disciplines in migration and mobility research : a practical and reflective account [PDF]

open access: yes
This working paper draws on the experiences of three scholars involved in the research project “Evolving (Im)Mobility Regimes: Migrant Workers’ Entitlement and Precarization in Times of Crisis”, conducted within the framework of the ‘nccr-on the move ...
Łysienia, Maja   +2 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

An analysis of moves, hedges, and boosters in applied linguistics research article abstracts of Thai international journals

open access: yesSocial Sciences and Humanities Open
A well-crafted research article abstract (RAA) can persuade journal editors to consider publishing the research by effectively highlighting the significance and quality of the study.
Phakhawadee Chaisiri   +2 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

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