Tracking Nano- and Microplastics in Plants: Uptake Pathways, Tissue Distribution, and Analytical Strategies from Microscopy to Spectroscopy. [PDF]
Maqsood A +3 more
europepmc +1 more source
Structure Validation: A Moving Target [PDF]
D. J. Watkin, R. Cooper, C. K. Prout
openaire +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
The AI-native health science institution innovation theater vs. structural redesign. [PDF]
Zhang J, Citardi MJ, Jiang X, Savitz S.
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
A thin robot made of flexible electronics for in-situ machining and inspection of large structures. [PDF]
Wang H +7 more
europepmc +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Opening the black box of mechanical insufflation-exsufflation: bringing upper airway physiology to the bedside. [PDF]
Crimi C, Impellizzeri P, Winck JC.
europepmc +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Ocular ultrasound: a clinical review for the medicine-trained intensivist. [PDF]
Slagle D, Adelman M, Talan J.
europepmc +1 more source

