Results 231 to 240 of about 4,488,461 (298)

The biosecurity busyness paradox: Why doing more and remaining consistent may be undermining global resilience. [PDF]

One Health
McDonald JI.
europepmc   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

RLBWT-based LCP computation in compressed space for terabase-scale pangenome analysis. [PDF]

Bioinformatics
Sanaullah A, Brown NK, Shakya P, Deegutla A, Naseri A, Langmead B, Zhi D, Zhang S.   +7 more
europepmc   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source

Phylo-Movies: animating phylogenetic trees from sliding-window analyses. [PDF]

Mol Biol Evol
Sakalli E, Haendeler S, von Haeseler A, Schmidt HA.   +3 more
europepmc   +1 more source

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus, Devin L. Brown, Bernadette Boden‐Albala   +2 more
wiley   +1 more source

Jump now, pay later: saltatory behavior trades off with body mass and facilitates shelter repair in a seed-dwelling insect. [PDF]

Naturwissenschaften
Palas K, Nusrath M, Tung DL, Volpe M, Martin AM, Swierk L.   +5 more
europepmc   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Structural insight into sodium-dependent bile acid transport by members of the SLC10 family. [PDF]

Structure
Li CY, Grob AA, Repa L, Huxley O, Brotherton DH, Becker P, Dadzie R, Beckstein O, Cameron AD.   +8 more
europepmc   +1 more source

How the brain dances across critical boundaries. [PDF]

PLoS Biol
Sederberg AJ.
europepmc   +1 more source