Results 111 to 120 of about 6,725,693 (341)
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Simulation of human movement and behaviour in crowded spaces using gaming software [PDF]
, 2013 This paper discusses the development of human movement and behaviour simulation in crowded spaces as part of the AUNT-SUE (Accessibility and User Needs in Transport for Sustainable Urban Environments) research project. The research starts with applying a
Case, Keith, Mohamaddan, Shahrol
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Acta Gymnica, 2015 Background: The research is based on an assumption that the hypokinesia induced by cerebral palsy (CP) leads to inhibition of some mental functions. The method we used to treat patients with CP, hippotherapy (HT), is a treatment using horses and belongs ...
Eva Krejčí +2 more
doaj +1 more source
A Low-Dimensional Model of Coordinated Eye and Head Movements [PDF]
, 1994 Eye and head movement data, were recorded under head fixed and head-free conditions, and compared with theoretical results obtained using a nonlinear model of eye-head coordination.
Clarke, A.H., Przybyszcwski, A.W.
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
The notion of Threshold: an investigation into conceptual accompaniment in Aristotle and Hegel
Conserveries Mémorielles, 2010 What is unique to the idea of a threshold is that it is a threshold’s proper definition to generate or signal an inevitable accompanying image of a surrounding boundary or a further field of exploration, even though these accompanying terms or images ...
Jason Carter
doaj
A Movement to Transform Foster Parenting [PDF]
, 2016 This report explores ways for public agencies to ensure that children receive the care they need by enlisting more volunteers to step forward as foster parents and by encouraging the extraordinary individuals who have already answered the call to ...
core
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source