Results 121 to 130 of about 1,511,765 (248)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Ultrasonographic Tongue Base Motion Does Not Correlate With Hypoglossal Nerve Stimulation Outcomes. [PDF]

Laryngoscope Investig Otolaryngol
Tschopp S, Janjic V, Caversaccio M, Borner U, Tschopp K.   +4 more
europepmc   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Visuomotor information drives interference between the hands more than dynamic motor information during bimanual reaching. [PDF]

Exp Brain Res
Desrochers PC, Brunfeldt AT, Kagerer FA.
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

A phenomenological approach to spastic movement disorders: an international expert panel consensus. [PDF]

J Neurol
Biering-Sørensen B, Wissel J, Rosales R, Reebye R, Jacinto J, Francisco GE, Sanderson P, Ertzgaard P.   +7 more
europepmc   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Intercepting moving targets: does the visuomotor latency depend on whether one taps on the target or slides through it? [PDF]

Exp Brain Res
Brenner E, Bom S, Smeets JBJ.
europepmc   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Clarifying space use concepts in ecology: Range vs. occurrence distributions. [PDF]

Ecology
Alston JM, Fleming CH, Noonan MJ, Tucker MA, Silva I, Folta C, Akre TSB, Ali AH, Belant JL, Beyer D, Blaum N, Böhning-Gaese K, de Paula RC, Dekker J, Drescher-Lehman J, Farwig N, Fichtel C, Fischer C, Ford AT, Janssen R, Jeltsch F, Kappeler PM, LaPoint SD, Markham AC, Medici EP, Morato RG, Nathan R, Olson KA, Patterson BD, Petroelje TR, Ramalho EE, Rösner S, Oliveira-Santos LGR, Schabo DG, Selva N, Sergiel A, Spiegel O, Ullmann W, Zięba F, Zwijacz-Kozica T, Wittemyer G, Fagan WF, Müller T, Calabrese JM.   +43 more
europepmc   +1 more source