Results 111 to 120 of about 5,493,552 (256)
Fine Structure of Plasmodesmata-Associated Membrane Bodies Formed by Viral Movement Protein. [PDF]
Plants (Basel), 2023 Atabekova AK +10 more
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Different Approaches For Protein Engineering In Industrial Biotechnology [PDF]
, 2011 Protein engineering is the novel field which has wide applications from pharmaceutics, industry, commercial, laundry and research. It may apply rational design or non rational design or both.
Muhammad Waheed Akhtar, Israr Khan
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
New Unity Movement Resolutions
, 2010 Resolutions taken at the Port Elizabeth Conference held on the 23-26/04/2010, focused on the following: health, nationalisation of the mines in South Africa, politics and the environment, 2010 world cup soccer, the social deficit and the struggle for ...
New Unity Movement
core
The Tomato Brown Rugose Fruit Virus Movement Protein Gene Is a Novel Microbial Source Tracking Marker. [PDF]
Appl Environ Microbiol, 2023 Natarajan A +18 more
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Gain-of-function mutant of movement protein allows systemic transport of a defective tobacco mosaic virus. [PDF]
iScience, 2022 Tran PT, Vo Phan MS, Citovsky V.
europepmc +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Expression, Purification, and Characterisation of South African Cassava Mosaic Virus Cell-to-Cell Movement Protein. [PDF]
Curr Issues Mol Biol, 2022 Nankoo N, Achilonu IA, Rey MEC.
europepmc +1 more source