Results 151 to 160 of about 7,916,685 (373)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Ions in Fluctuating Channels: Transistors Alive

, 2013
Ion channels are proteins with a hole down the middle embedded in cell membranes. Membranes form insulating structures and the channels through them allow and control the movement of charged particles, spherical ions, mostly Na+, K+, Ca++, and Cl ...
Barthel J., BOB EISENBERG, Corry B., Doi M., Eisenberg B., Engl H. W., Hyon Y., Nadler B., Riordan M., Schuss Z.   +9 more
core   +1 more source

The Tomato Brown Rugose Fruit Virus Movement Protein Gene Is a Novel Microbial Source Tracking Marker. [PDF]

Appl Environ Microbiol, 2023
Natarajan A, Fremin BJ, Schmidtke DT, Wolfe MK, Zlitni S, Graham KE, Brooks EF, Severyn CJ, Sakamoto KM, Lacayo NJ, Kuersten S, Koble J, Caves G, Kaplan I, Singh U, Jagannathan P, Rezvani AR, Bhatt AS, Boehm AB.   +18 more
europepmc   +1 more source

Mechanism of the serotonin effect on lung transvascular fluid and protein movement in awake sheep. [PDF]

, 1975
Kenneth L. Brigham, Patty Jill Owen
openalex   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Gain-of-function mutant of movement protein allows systemic transport of a defective tobacco mosaic virus. [PDF]

iScience, 2022
Tran PT, Vo Phan MS, Citovsky V.
europepmc   +1 more source

Potato virus X RNA-mediated assembly of single-tailed ternary 'coat protein-RNA-movement protein' complexes.

Journal of General Virology, 2006
Different models have been proposed for the nature of the potexvirus transport form that moves from cell to cell over the infected plant: (i) genomic RNA moves as native virions; or (ii) in vitro-assembled non-virion ribonucleoprotein (RNP) complexes ...
Olga Karpova, O. Zayakina, M. Arkhipenko, Eugene V. Sheval, O. I. Kiselyova, V. Y. Poljakov, I. Yaminsky, N. Rodionova, J. Atabekov   +8 more
semanticscholar   +1 more source

The inner centromere protein (INCENP) antigens: movement from inner centromere to midbody during mitosis. [PDF]

, 1987
Carol Cooke, Margarete M. S. Heck, William C. Earnshaw   +2 more
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Use of the Metropolis algorithm to simulate the dynamics of protein chains

, 2007
The Metropolis implementation of the Monte Carlo algorithm has been developed to study the equilibrium thermodynamics of many-body systems. Choosing small trial moves, the trajectories obtained applying this algorithm agree with those obtained by ...
Baillie, Brunger, Ding, Ding, Ding, Ding, Dokholyan, G. Tiana, Go, Irback, Kikuchi, L. Sutto, Lau, Levy, Meakin, Metropolis, Mirny, R.A. Broglia, Rey, Shakhnovich, Shimada, Shimada, van Kampen   +22 more
core   +1 more source