Results 111 to 120 of about 4,282,757 (297)

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

New Unity Movement Bulletin

, 2012
The Bulletin was the official newsletter of the New Unity Movement. It was published about twice a year and contained articles reflecting the organisation's views on resistance to the Apartheid ...

core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Effect on Independence for the Quantity on Displacement of the Center of Mass of a Mechanical System from Environmental Dissipativity (Savelkaev Effect)

Механика машин, механизмов и материалов, 2011
Theoretically proved that the displacement of the center of mass of a mechanical system for any of the corners of the counter rotational movement of its working bodies in the plane of the reference body independent of the resistance movement of the ...
S.V. Savelkaev
doaj  

Ethical Foreground and Background in Adult Educator Work

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

New Unity Movement Bulletin

, 1987
The Bulletin was the official newsletter of the New Unity Movement. It was published about twice a year and contained articles reflecting the organisation's views on resistance to the Apartheid ...

core   +1 more source

New Unity Movement Bulletin

, 2005
The Bulletin was the official newsletter of the New Unity Movement. It was published about twice a year and contained articles reflecting the organisation's views on resistance to the Apartheid ...

core  

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

THE COSTS ASSOCIATED WITH THE RESISTANCE MOVEMENT FROM TRACK

Nauka ta progres transportu, 2009
The procedure of determination of expenses related to the resistance to movement due to the track is presented.
R. S. Lipovskyi, M. I. Umanov, O. V. Gubar, O. S. Chernyshova   +3 more
doaj  

New Unity Movement Bulletin

, 2004
The Bulletin was the official newsletter of the New Unity Movement. It was published about twice a year and contained articles reflecting the organisation's views on resistance to the Apartheid ...

core