Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Reliable but Not Interchangeable: What Validated Instruments Measure When They Grade an Anastomosis. [PDF]
Carciumaru TZ +4 more
europepmc +1 more source
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Diagnostic Reasoning in General Internal Medicine Consultations: A Text Mining Analysis of Consultation Requests. [PDF]
Kawamura R, Harada Y, Shimizu T.
europepmc +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Anthropometric and Neuromuscular Characteristics of Breakers Across Different Performance Levels: An Exploratory Cross-Sectional Field-Based Study. [PDF]
Freitag N +5 more
europepmc +1 more source
Tuning Bond Exchange Rate to Control Long-Time Mobility and Creep in Vitrimer-like Networks. [PDF]
Mamat A +7 more
europepmc +1 more source
Correction: Li et al. High-Temperature Electrical Transport Behavior of p-Doped Boron Diamond Film/n-WS<sub>2</sub> Nanosheet Heterojunction. <i>Nanomaterials</i> 2025, <i>15</i>, 1900. [PDF]
Li C, Sang D, Shi Y, Ge S, Du L, Wang Q.
europepmc +1 more source
Editorial Comment to Feasibility and Safety of Repeat Robot-Assisted Partial Nephrectomy for Ipsilateral Local Recurrence: A Case Series. [PDF]
Yoshida K, Takagi T.
europepmc +1 more source

