Results 81 to 90 of about 533,875 (268)
SAMS - Sharing Awareness Moves Safety
Maintenance, preserving well-established status, and changes, which constitute the basis for innovation and improvement, are the daily business of all employees responsible for process plants.
J. Sommer
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
2002 in the MOVES Institute [PDF]
The MOVES Institute’s mission is research, application, and education in the grand challenges of modeling, virtual environments, and simulation. Our specialties are 3D visual simulation, networked virtual environments, computer-generated autonomy, human ...
Zyda, Michael
core +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Rhetorical Move Analysis of Abstracts in Costa Rican TEFL Undergraduate Theses
s are an important part of an academic document, but traditionally have been neglected in undergraduate theses in the English teaching major. This investigation aimed to explore the following interrogatives in the Costa Rican higher education context: (1)
Graciela Ferreiro-Santamaria
doaj
The COVID-19 pandemic has deeply impacted the field of education, shifting instruction from in-person classrooms to virtual learning environments on a global scale.
Kevin Wong +2 more
doaj +1 more source
The role of mass protest has been recurrently central yet controversial in the American culture. Central because American history presents a constellation of significant collective protest movements, very different among them but generally symptomatic ...
Nicola Paladin
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source

