Results 101 to 110 of about 1,101,560 (296)

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Dynamic Contact Analysis of Flexible Telescopic Boom Systems with Moving Boundary

open access: yesMathematics
A flexible telescopic boom is a multi-body system composed of several hollow booms nestled into each other. For this kind of system, due to the limitation of the elemental size being fixed, it is necessary to divide it into many small-sized elements and ...
Tianjiao Zhao, Zhaohui Qi, Tianyu Wang
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Implementation and Validation of Explicit Immersed Boundary Method and Lattice Boltzmann Flux Solver in OpenFOAM

open access: yesDynamics
In this work, the explicit boundary-condition-enforced immersed boundary method (EIBM) and the lattice Boltzmann flux solver (LBFS) are integrated into OpenFOAM to efficiently solve incompressible flows with complex geometries and moving boundaries.
Yangyang Liu   +3 more
doaj   +1 more source

Simulation of continuously deforming parabolic problems by Galerkin finite-elements method

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1986
A general numerical finite element scheme is described for parabolic problems with phase change wherein the elements of the domain are allowed to deform continuously.
Yahia S. Halabi
doaj   +1 more source

Moving holographic boundaries

open access: yesNuclear Physics B
v5: typos fixed; appendix added; improved presentation; no changes on ...
openaire   +4 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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