Results 111 to 120 of about 2,241,835 (296)

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Synthesis of Control of Terminal Acceleration of Spatial Rotations [PDF]

open access: yes
Among the problems of Adaptive Terminal Control, one of the most important is the problem of control of acceleration process of moving objects. Two cases are discussed: Control with arbitrary terminal acceleration and control with certain value of ...
Cabir Ergüven
core  

An Improved YOLOv8 to Detect Moving Objects

open access: yesIEEE Access
Deep learning has revolutionized object detection, with YOLO (You Only Look Once) leading in real-time accuracy. However, detecting moving objects in visual streams presents distinct challenges. This paper proposes a refined YOLOv8 object detection model,
Mukaram Safaldin   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Moving object detection using registration for a moving camera platform [PDF]

open access: yes, 2012
In this research work, an accurate and fast moving object detector that can detect all the moving objects from Unmanned Aerial Platform (UAV) is proposed.
Cheraghi, Seyed Ali
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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