Results 171 to 180 of about 4,251,152 (284)

The Selenium Paradox: From Evolutionary Redox Chemistry to Medicinal Chemistry. [PDF]

Int J Mol Sci
Proto M, Giraldi C, Santi C.
europepmc   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Comparative Evaluation of Bandit-Style Heuristic Policies for Moving Target Detection in a Linear Grid Environment. [PDF]

Sensors (Basel)
Kang H, Ahn M, Seo Y.
europepmc   +1 more source

Bistable Networks Enable Complex Shape Changes

Advanced Science, EarlyView.
Transition‐controlled metamaterials are networks of bistable mechanical memory that store local binary states and express them as global shape change. By decoupling low‐force programming from high‐force holding, a single lattice is reconfigured into distinct 2D profiles and 3D surfaces without continuous actuation, enabling reusable morphing materials ...
Sawyer Thomas, Jeffrey Lipton
wiley   +1 more source

Hormone priming and metabolic engineering of phytohormone crosstalk in rice under combined biotic and abiotic stresses: a multi-omics perspective for climate-resilient crop development. [PDF]

Front Plant Sci
Shuixing Z, Jing Z, Alshehri D, Al-Amrah H, Manzoor I, Aiying Y.   +5 more
europepmc   +1 more source

Interference of ATP‐Binding Cassette Transporter by Functional Nano‐Delivery System for High Efficiency Management of Insecticide‐Resistant Nilaparvata lugens

Advanced Science, EarlyView.
A ZIF‐90 nanocarrier delivers dinotefuran and suppresses NlABCG3 and NlABCH1 in resistant Nilaparvata lugens. This system combines pH/ATP‐triggered release with enhanced foliar retention, improving efficacy while sparing honeybees and promoting rice growth, offering a promising resistance‐breaking strategy.
Chengshuai He, Hejun Ren, Shuo Zhang, Jikang Cheng, Hui Zhang, Jiao Liu, Sijie Wang, Congfen Gao, Yanchao Zhang, Yunhao Gao   +9 more
wiley   +1 more source

Truth, tone, and trust: integrating an AI exercise to foster responsible science communication in a graduate biomedical science course. [PDF]

J Microbiol Biol Educ
Ciubotariu II, Bosch G.
europepmc   +1 more source

PSO-based Moving Target Defense for Enhanced False Data Injection Attack Prevention in Smart Grids

PSO-based Moving Target Defense for Enhanced False Data Injection Attack Prevention in Smart ...
A Srivastava (9894239), A Pal (7768769), S Pol (22748924), M Mouhammadpourfard (22748921), Adnan Anwar (13055967)   +4 more
core  

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

Advanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source

Chemical Signaling and Integrated Strategies for Biological Control in Crop Agroecosystems. [PDF]

Insects
Ahmad S, Chen D, Cen Y, Jamil M, Gul H, Palma-Onetto V, Ouyang G, Xiang M.   +7 more
europepmc   +1 more source