Results 81 to 90 of about 21,247 (273)

Computational Modelling of Cerebral Blood Flow Rate at Different Stages of Moyamoya Disease in Adults and Children

Bioengineering, 2023
Moyamoya disease is a cerebrovascular disorder which causes a decrease in the cerebral blood flow rate. In this study, a lumped parameter model describing the pressures and flow rates in the heart chambers, circulatory system, and cerebral circulation ...
Surhan Bozkurt, Selim Bozkurt
doaj   +1 more source

Doença de Moyamoya: relato de três pacientes brasileiros [PDF]

, 1999
Moyamoya disease (MMD) is a chronic occlusive cerebrovascular disease of unknown etiology reported mainly in the Japanese. Most cases occur in children. The disease is rare in non-Oriental adults manifesting itself mostly as intracerebral hemorrhages. We
Franco, Clélia Maria Ribeiro, Fukujima, Marcia Maiumi, Gabbai, Alberto Alain, Oliveira, Roberto de Magalhães Carneiro de   +3 more
core   +3 more sources

Achieving robust labeling above the circle of Willis with vessel‐encoded arterial spin labeling

Magnetic Resonance in Medicine, Volume 94, Issue 4, Page 1415-1431, October 2025.
Abstract Purpose To improve the robustness of noninvasive vessel‐selective perfusion imaging and angiography using vessel‐encoded arterial spin labeling (VEASL) when applied to complex vascular geometries, such as above the circle of Willis (CoW) in the brain.
Hongwei Li, Yang Ji, He Wang, Zhensen Chen, Tiansheng Qian, Yujun Liao, Jian Wang, Joseph G. Woods, Yuriko Suzuki, Thomas W. Okell   +9 more
wiley   +1 more source

Arterial spin labelling MRI for assessment of cerebral perfusion in children with moyamoya disease: comparison with dynamic susceptibility contrast MRI [PDF]

, 2018
Introduction: This study seeks to evaluate the diagnostic accuracy of cerebral perfusion imaging with arterial spin labelling (ASL) MR imaging in children with moyamoya disease compared to dynamic susceptibility contrast (DSC) imaging.
Goetti, Robert, Kellenberger, Christian, Khan, Nadia, O'Gorman, Ruth, Scheer, Ianina   +4 more
core  

Chronic cerebral hypoperfusion‐induced myelin loss in normal‐appearing white matter correlates with cognitive decline: insights from moyamoya disease

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 11, Issue 4, October-December 2025.
Abstract INTRODUCTION Chronic cerebral hypoperfusion (CCH)‐induced white matter hyperintensities (WMHs) are a well‐established risk factor for cognitive impairment and dementia. While animal and post mortem studies suggest that myelin loss in normal‐appearing white matter (NAWM) precedes WMHs, in vivo evidence in human brain remains limited.
Xinfeng Yu, Duo Xu, Yannan Yu, Junwen Hu, Lin Wang, Biao Jiang, Minming Zhang   +6 more
wiley   +1 more source

Genetic analysis of RNF213 p.R4810K variant in non-moyamoya intracranial artery stenosis/occlusion disease in a Chinese population

Environmental Health and Preventive Medicine, 2017
Objectives RNF213 p.R4810K was identified as a susceptibility variant for moyamoya disease in Asia and non-moyamoya intracranial artery stenosis/occlusion disease in Japan and Korea recently.
Tong Zhang, Congrong Guo, Xin Liao, Jian Xia, XiaoXiao Wang, Jing Deng, Junxia Yan   +6 more
doaj   +1 more source

Defining the phenotypes of sickle cell disease. [PDF]

, 2011
The sickle cell gene is pleiotropic in nature. Although it is a single gene mutation, it has multiple phenotypic expressions that constitute the complications of sickle cell disease.
Albers GW, Ballas SK, Ballas SK, Ballas SK, Ballas SK, Ballas SK, Banerjee S, Bellomo R, Bookchin RM, Brazier DJ, Dana MR, DeBaun MR, DeBaun MR, Dobson SR, Goldberg MF, Halabi-Tawil M, Hatton CS, Johnson CS, Karam LB, Koshy M, Ohene-Frempong K, Pearson HA, Powars D, Powell RW, Robertson KD, Rogers ZR, Samir K. Ballas, Shao SH, Vichinsky EP, Vichinsky EP, Vichinsky EP, West MS, Williams GC, Zimmerman SA   +33 more
core   +2 more sources

Clinically relevant niclosamide concentrations modulate TMEM16A and CaV1.2 channels to control artery tone and capillary diameter

British Journal of Pharmacology, Volume 182, Issue 19, Page 4490-4515, October 2025.
Abstract Background and Purpose TMEM16A Ca2+‐gated Cl− channels mediate depolarisation of contractile vascular cells. The anthelmintic niclosamide was reported to modulate the TMEM16A channel, suggesting possible repurposing for vascular pharmacology. Here, we investigate the mechanism of TMEM16A modulation by niclosamide and explore its effect on the ...
Rachel Kaye, Claire Pearson, Tibyan Babiker, Emilio Agostinelli, Rumaitha Al‐Hosni, Paolo Tammaro   +5 more
wiley   +1 more source

A STOP‐Gain RNF213 Variant Causes Chorea, Stroke‐Like Episodes, and Leigh Syndrome‐Like Encephalopathy

Movement Disorders, EarlyView.
Roberta Bovenzi, Mariasavina Severino, Jennifer Nichols, Fred Shen, Ignacio J. Keller Sarmiento, Bernabe I. Bustos, Lisa Kinsley, Dimitri Krainc, Niccolò E. Mencacci   +8 more
wiley   +1 more source

Serum Vitamin D Levels Were Not Associated With the Risk of Aneurysmal Subarachnoid Hemorrhage: A Large Cohort Study With Propensity Score Matching and Mendelian Randomization Analysis

CNS Neuroscience &Therapeutics, Volume 31, Issue 10, October 2025.
No significant association or causal relationship was observed between serum vitamin D levels and aneurysmal subarachnoid hemorrhage (aSAH). ABSTRACT Background Vitamin D (VitD) may protect arterial health, but its link to cerebral aneurysm rupture remains unclear. This study aims to investigate the correlation between serum VitD levels and the risk of
Haoran Qiu, Kai Chen, Yang Yu, Ziyin Song, Jingzheng Liu, Lvyin Luo, Xinlong Ma, Zhaoyang Yuan, Maogui Li, Jianfeng Zhuang, Mingxiang Zhang, Wandong Su, Yunyan Wang, Donghai Wang, Weiying Zhong   +14 more
wiley   +1 more source