Results 151 to 160 of about 5,276 (179)

Radiation-induced and neurofibromatosis-associated malignant peripheral nerve sheath tumors (MPNST) have worse outcomes than sporadic MPNST

Radiotherapy and Oncology, 2019
Malignant peripheral nerve sheath tumors (MPNST) may be sporadic or associated with neurofibromatosis or prior radiation. MPNST may behave aggressively with a high rate of local recurrence and distant metastasis.In an IRB approved protocol, we reviewed the clinical characteristics, treatment, and outcomes of 280 patients treated for MPNST at ...
Ruoyu Miao, Haotong Wang, Alex Jacobson, Anna P. Lietz, Edwin Choy, Kevin A. Raskin, Joseph H. Schwab, Vikram Deshpande, G. Petur Nielsen, Thomas F. DeLaney, Gregory M. Cote, Francis J. Hornicek, Yen-Lin E. Chen   +12 more
openaire   +2 more sources

Differences between neurofibromatosis-1-associated malignant peripheral nerve sheath tumors (MPNST) and sporadic MPNST: The Mayo Clinic experience.

Journal of Clinical Oncology, 2011
10066 Background: Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disorder associated with several clinical manifestations, including peripheral neurofibromas. Malignant transformation of these neurofibromas into malignant peripheral nerve sheath tumors (MPNST) is a potential life-threatening sequelae of this syndrome.
K. N. Johnson, C. H. Stucky, B. A. Pockaj, R. J. Gray, P. S. Rose, N. Wasif   +5 more
openaire   +1 more source

Malignant Peripheral Nerve Sheath Tumor (MPNST)

1999
This usually high-grade sarcoma mainly consists of spindle cells of both schwannian and fibroblastic type, and occasionally may have focal heterogeneous differentiation, such as chondroid, osteoid, rhabdomyoblastic, epithelial, endothelial, and melanocytic. This histology recapitulates the components of the nerve sheath (Schwann cells and fibroblasts),
openaire   +1 more source

TRPS1 expression in MPNST is correlated with PRC2 inactivation and loss of H3K27me3

Human Pathology
Initially described as a highly specific immunohistochemical marker for carcinomas of mammary origin, trichorhinophalangeal syndrome type 1 (TRPS1) has subsequently been detected in a variety of other non-mammary tumors. In this study, we examined the immunohistochemical expression of TRPS1 in 114 peripheral nerve sheath tumors, including 43 malignant ...
Rossana Lazcano, Davis R. Ingram, Gauri Panse, Alexander J. Lazar, Wei-Lien Wang, Jeffrey M. Cloutier   +5 more
openaire   +2 more sources

Stem-like cells drive NF1-associated MPNST functional heterogeneity and tumor progression

Cell Stem Cell, 2021
Jack Shern, Sameer Farouk Sait, Xuanhua Xie   +2 more
exaly  

PNET vs MPNST

The American Journal of Surgical Pathology, 1993
openaire   +1 more source

Surgical strategies and the use of functional reconstructions after resection of MPNST

Orthoplastic Surgery, 2021
Cornelis Verhoef, Jh Coert, Winan Van Houdt   +2 more
exaly  

COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF MPNST

2022
HAO HUAIXIANG, MOODY SUSAN ELIZABETH, PRATILAS CHRISTINE A, WANG JIAWAN   +3 more
openaire   +2 more sources

56. Chr8 gain is associated with MPNST transformation

Cancer Genetics, 2022
openaire   +1 more source

Potential of boron neutron capture therapy (BNCT) for malignant peripheral nerve sheath tumors (MPNST)

Applied Radiation and Isotopes, 2015
Hiroshi Moritake, Tamotsu Takeuchi, Minoru Suzuki   +2 more
exaly