Doxorubicin-Loaded Human Serum Albumin Submicron Particles: Preparation, Characterization and In Vitro Cellular Uptake [PDF]
, 2020 Doxorubicin (DOX) is an effective anthracycline antibiotic drug which is commonly used in a broad range cancer therapy. However, due to dose depending side effects and toxicity to non-cancerous tissues, its clinical applications are restricted.
Bäumler, Hans +7 more
core +1 more source
Orphanet Journal of Rare Diseases, 2021 Managed access agreements provide a crucial mechanism whereby real-world data can be collected systematically to reduce uncertainty around available clinical and economic data, whilst providing the opportunity to identify patient sub-populations who are ...
Bob Stevens +5 more
doaj +1 more source
Orphanet Journal of Rare Diseases, 2019 Background Mucopolysaccharidosis type VII (Sly disease, MPS VII), is an ultra-rare, multi-symptom disease with variable clinical presentations which can present challenges with diagnosis, management and care.
Alexandra Morrison +4 more
doaj +1 more source
The Thouless theorem for matrix product states and subsequent post-density matrix renormalization group methods [PDF]
, 2013 The similarities between Hartree-Fock (HF) theory and the density-matrix renormalization group (DMRG) are explored. Both methods can be formulated as the variational optimization of a wave-function ansatz.
Chan, Garnet Kin-Lic +3 more
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Elevated cerebral spinal fluid biomarkers in children with mucopolysaccharidosis I-H. [PDF]
, 2016 Mucopolysaccharidosis (MPS) type-IH is a lysosomal storage disease that results from mutations in the IDUA gene causing the accumulation of glycosaminoglycans (GAGs).
Dickson, Patricia I +6 more
core +1 more source
Up and away: ontogenic transference as a pathway for aerial dispersal of microplastics [PDF]
, 2018 Microplastics (MPs) are ubiquitous pollutants found in marine, freshwater and terrestrial ecosystems. With so many MPs in aquatic systems it is inevitable that they will be ingested by aquatic organisms, and be transferred up through the food chain ...
Amanda Callaghan +7 more
core +2 more sources
Defects in the medial entorhinal cortex and dentate gyrus in the mouse model of Sanfilippo syndrome type B. [PDF]
, 2011 Sanfilippo syndrome type B (MPS IIIB) is characterized by profound mental retardation in childhood, dementia and death in late adolescence; it is caused by deficiency of α-N-acetylglucosaminidase and resulting lysosomal storage of heparan sulfate.
Neufeld, Elizabeth F +2 more
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Algebraic Geometry of Matrix Product States [PDF]
, 2014 We quantify the representational power of matrix product states (MPS) for entangled qubit systems by giving polynomial expressions in a pure quantum state's amplitudes which hold if and only if the state is a translation invariant matrix product state or
Critch, Andrew, Morton, Jason
core +4 more sources
Poly(2-propylacrylic acid)/poly(lactic-co-glycolic acid) blend microparticles as a targeted antigen delivery system to direct either CD4+ or CD8+ T cell activation. [PDF]
, 2017 Poly(lactic-co-glycolic acid) (PLGA) based microparticles (MPs) are widely investigated for their ability to load a range of molecules with high efficiency, including antigenic proteins, and release them in a controlled manner.
Bracho-Sanchez, Evelyn +6 more
core +1 more source
Numerical analysis of fluid lubrication in line contact by using the MPS method
Nihon Kikai Gakkai ronbunshu, 2020 The fluid film lubrication problem is usually solved using classical Reynolds equation-based modeling to predict fluid film behavior such as pressure distribution and oil film thickness, which requires pressure boundary conditions at the locations of ...
Hideyo NEGISHI +5 more
doaj +1 more source