Trehalose-mediated activation of Mitf corrects autophagy defects and ameliorates neurodegeneration in MPS VII [PDF]
Apurba Das, Rupak Datta
openalex +1 more source
Traditional 16S rRNA gene and Internal Transcribed Spacer region amplicon sequencing provides only relative abundance, often leading to biased ecological interpretations. To overcome this limitation, we developed Accu16S/AccuITS, an absolute quantification method for bacterial and fungal amplicons based on synthetic internal spike‐in DNA with known ...
Defeng Bai +10 more
wiley +1 more source
Synthetic aptamer mechanoreceptors enable cell-specific force sensing and temporal control via DNA circuits. [PDF]
Xu T, Sethi S, Drees C, Walther A.
europepmc +1 more source
Engineering Topological Phases with a Traveling‐Wave Spacetime Modulation
Time‐varying systems have garnered considerable attention due to their unique potential in manipulating electromagnetic waves. Here, a novel class of topological spacetime crystals with a traveling‐wave modulation is introduced. By manipulating material anisotropy, one can engineer light angular momentum and non‐trivial topological phases characterized
João C. Serra, Mário G. Silveirinha
wiley +1 more source
Optical Skyrmions with Tunable or Reconfigurable Topology Using Spin‐Decoupled Metaoptics
The work introduces advanced optical elements capable of generating and dynamically reconfiguring complex light patterns known as optical skyrmions. By precisely shaping light polarization at the nanoscale, a single engineered metasurface can generate and manipulate robust and tunable polarization textures in an efficient and scalable way.
Andrea Vogliardi +5 more
wiley +1 more source
Hydrolysis of PET in the solid generates nanoparticles, but thermal signatures of PET were only observed for hydrolysis at 150°C, while oligomers appeared to dominate the non‐monomeric products from hydrolysis at higher temperatures. ABSTRACT Circularity in plastic waste management through depolymerization to monomer is a promising route to address ...
Sierra F. Yost +4 more
wiley +1 more source
Limited Potential of Polystyrene Microplastic as a Vector of Microcystin-LR in Diluted Lysate of <i>Microcystis aeruginosa</i> Strain MASH01-A05 in Laboratory Freshwater and Brackish Water Conditions. [PDF]
Sharmin S +6 more
europepmc +1 more source
The future of artificial intelligence and the mathematical and physical sciences (AI+MPS) [PDF]
Andrew Ferguson +6 more
openalex +1 more source
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu +4 more
wiley +1 more source

