Results 41 to 50 of about 5,581,531 (332)

Improved treatment of colorectal liver metastases by early response evaluation and regimen adjustment: a prospective study of clinical functional MR-based modeling

Cancer Biology & Medicine
Objective: The aim of the study was to evaluate the feasibility of functional MR in predicting the clinical response to chemotherapy in patients with colorectal liver metastases (CLM).
Wenhua Li, Huan Zhang, Zhe Gong, Yue Li, Zhiyu Chen, Xiaodong Zhu, Mingzhu Huang, Zhe Zhang, Chenchen Wang, Lixin Qiu, Qirong Geng, Jinjia Chang, Xiaoying Zhao, Xuedan Sheng, Wen Zhang, Tong Tong, Weijian Guo   +16 more
doaj   +1 more source

MR-Compatible Compression Device for In-Vitro Evaluation of Biomechanical Properties of Cartilage

Journal of Biomechanical Science and Engineering, 2008
Objective: Purpose of the paper is to present and validate a device for cartilage compression for assessment of MR parameters (T1, T2, ADC) in cartilage explants before, during and after compression operating with novel features. Design: This device fits
Vladimir JURAS, Pavol SZOMOLANYI, Zuzana MAJDISOVA, Siegfried TRATTNIG   +3 more
doaj   +1 more source

Magnetoresistance Effects in SrFeO(3-x): Dependence on Phase Composition and Relation to Magnetic and Charge Order

, 2005
Single crystals of iron(IV) rich oxides SrFeO(3-x) with controlled oxygen content have been studied by Moessbauer spectroscopy, magnetometry, magnetotransport measurements, Raman spectroscopy, and infrared ellipsometry in order to relate the large ...
A. Lebon, A. Maljuk, A. V. Boris, B. Keimer, C. Bernhard, C. Bernhard, C. T. Lin, C. Ulrich, H. Oda, P. Adler, T. Takeda, V. Damljanović   +11 more
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Multimodality MRI Radiomics Based on Machine Learning for Identifying True Tumor Recurrence and Treatment-Related Effects in Patients with Postoperative Glioma

Neurology and Therapy, 2023
Introduction Conventional magnetic resonance imaging (MRI) features have difficulty distinguishing glioma true tumor recurrence (TuR) from treatment-related effects (TrE).
Jinfa Ren, Xiaoyang Zhai, Huijia Yin, Fengmei Zhou, Ying Hu, Kaiyu Wang, Ruifang Yan, Dongming Han   +7 more
doaj   +1 more source

Integrated optimization of geometrical parameters and flow variables for industrial incinerator performance improvement

Results in Engineering, 2023
Industrial incinerators play a vital role in waste disposal, yet their operations carry significant environmental and efficiency consequences. The current study aimed to optimize an industrial incinerator using a multi-objective algorithm in which the ...
Mohammadhossein Hadadiyan, Hamed Arjmandi, Ousmane Abderrahmane Deme, Mohammad Javad Eghbali   +3 more
doaj   +1 more source

EVOLUTIONARY STABLE PROPERTIES OF POLITICAL PARTIES IN INDONESIA [PDF]

, 2004
The major idea is to use memetics as an analytical tool on viewing how the existing political parties towards General Election 2004 creating formation of their presidential candidacy, ideology behind it, the change of political atmosphere it will bring ...
Khanafiah, Mr Deni, Sartika, Mr Tiktik, Situngkir, Mr Hokky   +2 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Social consequences of Tūhoe migration: Voices from home in Te Urewera [PDF]

, 2008
A previous study by Nikora, Guerin, Rua & Te Awekotuku (2004) of the social consequences of Tūhoe moving to the Waikato region found employment and a tertiary education to be the primary motivators.
Guerin, Bernard, McCaughey, Jane, Nikora, Linda Waimarie, Rua, Mohi, Te Awekotuku, Ngahuia   +4 more
core   +1 more source