Results 51 to 60 of about 5,611,148 (333)

MR-Compatible Compression Device for In-Vitro Evaluation of Biomechanical Properties of Cartilage

Journal of Biomechanical Science and Engineering, 2008
Objective: Purpose of the paper is to present and validate a device for cartilage compression for assessment of MR parameters (T1, T2, ADC) in cartilage explants before, during and after compression operating with novel features. Design: This device fits
Vladimir JURAS, Pavol SZOMOLANYI, Zuzana MAJDISOVA, Siegfried TRATTNIG   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Integrated optimization of geometrical parameters and flow variables for industrial incinerator performance improvement

Results in Engineering, 2023
Industrial incinerators play a vital role in waste disposal, yet their operations carry significant environmental and efficiency consequences. The current study aimed to optimize an industrial incinerator using a multi-objective algorithm in which the ...
Mohammadhossein Hadadiyan, Hamed Arjmandi, Ousmane Abderrahmane Deme, Mohammad Javad Eghbali   +3 more
doaj   +1 more source

Social consequences of Tūhoe migration: Voices from home in Te Urewera [PDF]

, 2008
A previous study by Nikora, Guerin, Rua & Te Awekotuku (2004) of the social consequences of Tūhoe moving to the Waikato region found employment and a tertiary education to be the primary motivators.
Guerin, Bernard, McCaughey, Jane, Nikora, Linda Waimarie, Rua, Mohi, Te Awekotuku, Ngahuia   +4 more
core   +1 more source

Bipolar-Driven Large Magnetoresistance in Silicon

, 2013
Large linear magnetoresistance (MR) in electron-injected p-type silicon at very low magnetic field is observed experimentally at room temperature. The large linear MR is induced in electron-dominated space-charge transport regime, where the magnetic ...
A. B. Pippard, E. I. Karakushan, Eiji Shikoh, M. A. Lampert, Masashi Shiraishi, Michael P. Delmo, N. W. Ashcroft, R. S. Popovic, S. M. Sze, Teruya Shinjo   +9 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Multimodality MRI Radiomics Based on Machine Learning for Identifying True Tumor Recurrence and Treatment-Related Effects in Patients with Postoperative Glioma

Neurology and Therapy, 2023
Introduction Conventional magnetic resonance imaging (MRI) features have difficulty distinguishing glioma true tumor recurrence (TuR) from treatment-related effects (TrE).
Jinfa Ren, Xiaoyang Zhai, Huijia Yin, Fengmei Zhou, Ying Hu, Kaiyu Wang, Ruifang Yan, Dongming Han   +7 more
doaj   +1 more source

Large negative magnetoresistance in a ferromagnetic shape memory alloy : Ni_{2+x}Mn_{1-x}Ga

, 2005
5% negative magnetoresistance (MR) at room temperature has been observed in bulk Ni_{2+x}Mn_{1-x}Ga. This indicates the possibility of using Ni_{2+x}Mn_{1-x}Ga as magnetic sensors. We have measured MR in the ferromagnetic state for different compositions
Barman, S. R., Biswas, C., Rawat, R.
core   +1 more source

Magnetorheological landing gear: 1. A design methodology [PDF]

, 2007
Aircraft landing gears are subjected to a wide range of excitation conditions, which result in conflicting damping requirements. A novel solution to this problem is to implement semi-active damping using magnetorheological (MR) fluids.
Batterbee, D.C., Sims, N.D., Stanway, R., Wolejsza, Zbigniew   +3 more
core   +1 more source