Results 71 to 80 of about 5,581,531 (332)

Failure and Stress Analysis of Glass Fiber Reinforced Laminated Composite Pinned Joints [PDF]

International Journal of Advanced Design and Manufacturing Technology, 2013
In this study, behavior of pin-loaded glass fiber reinforced with polyethylene laminated composites with different stacking sequence and different dimensions has been observed experimentally and stress analysis was performed using ANSYS software. The aim
Suresh Babu Valeru, Tarasasanka Cherukuri   +1 more
doaj  

Distinct brain structural abnormalities in attention-deficit/hyperactivity disorder and substance use disorders: A comparative meta-analysis

Translational Psychiatry, 2022
As two common mental disorders during the period of adolescence that extend to early adulthood, attention-deficit/hyperactivity disorder (ADHD) and substance use disorders (SUDs) have considerable diagnostic co-occurrence and shared neuropsychological ...
Yajing Long, Nanfang Pan, Shiyu Ji, Kun Qin, Ying Chen, Xun Zhang, Min He, Xueling Suo, Yifan Yu, Song Wang, Qiyong Gong   +10 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Occupational triangular fibrocartilage complex injury in a sewing machine operator

Arhiv za Higijenu Rada i Toksikologiju
Triangular fibrocartilage complex (TFCC) injuries are associated with repetitive wrist movements and have mostly been reported in athletes but not in sewing machine operators, even though their jobs involve repetitive wrist movements.
Şahin Elif Reyhan, Kahraman Mustafa
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Exchange bias effect and intragranular magnetoresistance in Nd$_{0.84}Sr_{0.16}CoO_3

, 2009
Electrical transport properties as a function of magnetic field and time have been investigated in polycrystalline, Nd_{0.84}Sr_{0.16}CoO_3. A strong exchange bias (EB) effect is observed associated with the fairly large intragranular magnetoresistance ...
Huang W G, M Patra, Mydosh J A, Nogues J, Patra M, Patra M, S Giri, S Majumdar, Thakur M   +8 more
core   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Property as Constitutional Myth: Utilities and Dangers [PDF]

, 2003
The ability to perform everyday life occupations is a critical component in both evaluation and intervention for persons with mental retardation (MR). While the ability to perform personal and instrumental activities of daily living (ADL) has always been
Underkuffler, Laura S.
core   +1 more source