Results 211 to 220 of about 96,614 (276)

Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection

PROTEOMICS, EarlyView.
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren, Kenneth Weke, Darryl Hardie, Mariya I. Goncheva, Ted Hupp, Javier Antonio Alfaro, Helena Pětrošová, David R. Goodlett   +7 more
wiley   +1 more source

Utility of Far-Field Potentials as a Biomarker of Neurodegeneration in Spinal Muscular Atrophy. [PDF]

Muscle Nerve
Calma AD, Pavey N, Silva CS, Tsuji Y, Ghapar AA, Morris K, Kiernan MC, Farrar MA, Menon P, Vucic S.   +9 more
europepmc   +1 more source

Water Losses and Environmental Efficiency in Urban Water Supply Systems: A Comparative Assessment for Spain and Portugal

Sustainable Development, EarlyView.
ABSTRACT Water losses are a critical environmental and operational challenge, especially in regions exposed to increasing water stress. This study assesses the environmental productivity of municipal water supply services in Spain and Portugal during the period 2014–2022, explicitly treating losses as an undesirable output.
Elisabet Zafra Gómez, Emilio José de la Higuera Molina, Rui Cunha Marques, Cristina María Campos Alba, Pablo Povedano‐Fernández   +4 more
wiley   +1 more source

Clinical and electrophysiological features for differentiating MMN from hand-onset ALS. [PDF]

J Chin Med Assoc
Fang SY, Jih KY, Chao YC, Sytwu HP, Shih YC, Liao YC, Lee YC, Lee YC.   +7 more
europepmc   +1 more source

Ultrasensitive Detection of Neurofilament Light in Plasma Using F(Ab’)2‐Modified Graphene Field‐Effect Biosensor

Small, EarlyView.
An antibody fragment (F(ab')2)‐modified graphene field‐effect transistor biosensor is developed for the ultrasensitive detection of neurofilament light chain in clinical plasma. By reducing the Debye screening effect, the platform achieves a 114% sensitivity increase and a fivefold lower detection limit compared to whole‐antibody approaches ...
Selvinaz Burcu Kizilates, Rica Asrosa, Lenart Senicar, Anuja Sharma, Seda Gungordu Er, Nisha Naeem, Ahmad Nizamuddin bin Muhammad Mustafa, Yang Wu, Neil Graham, Amanda Heslegrave, Mohan Edirisinghe, Antonio Lombardo, Elias Torres, Henrik Zetterberg, Sami Ramadan, David J. Sharp, Bing Li   +16 more
wiley   +1 more source

Force Spectroscopy by Atomic Force Microscopy as Indicator for Cellular Microplastic Uptake. [PDF]

Int J Mol Sci
Kolesnik T, Öhlinger K, Absenger-Novak M, Fröhlich E.   +3 more
europepmc   +1 more source

BODIPY Photocage‐Based Injectable Hydrogel for Light‐Controlled Nanoparticle Release

Small, EarlyView.
This work presents an injectable hydrogel formulation which undergoes efficient photodegradation under green light irradiation. The gel can be easily injected to subcutaneous tissue through 23G needles, co‐encapsulate and photo‐release nanoparticles as well as exhibits excellent biocompatibility, making it promising for the development of light ...
Baihao Shao, David J. Peeler, Thomas F. F. Fernandez Debets, Jonathan P. Wojciechowski, Yue Shao, Yuxi Cheng, Kun Zhou, Robin J. Shattock, Molly M. Stevens   +8 more
wiley   +1 more source

Methodologies and methods for the development, evaluation and implementation of psychosocial interventions for dementia: protocol for a scoping review. [PDF]

BMJ Open
D'Andrea F, Bartels SL, Markaryan M, Masterson-Algar P, Bernal AN, De Bruin SR, Chirico I, Flynn A, Garcia L, Gebhard D, Handley M, Janssen N, Roes M, Stephens N, Teesing G, Van den Block L, Windle K, Moniz-Cook E, Graff M.   +18 more
europepmc   +1 more source

Addressing the Challenges of Translating LRRK2 Biology into Disease‐Modifying Therapies: The LRRK2 Investigative Therapeutics Exchange Initiative

Movement Disorders, EarlyView.
Esther Sammler, Francesca Tonelli, Michelle Durborow, Jim McNasby, Todd Sherer, Mahmood Ahmed, Stevan W. Djuric, Kalpana Merchant, Alastair Reith, Darryle Schoepp, Christine Klein, Shalini Padmanabhan, Dario R. Alessi   +12 more
wiley   +1 more source

Paired CycleGAN‐based virtual staining for 3D X‐ray histology of bone‐implant systems

Journal of Synchrotron Radiation, EarlyView.
This work demonstrates virtual staining for 3D X‐ray histology using a modified CycleGAN trained on paired synchrotron radiation microtomography (SR‐µCT) and histology images of bone‐implant specimens. The method enables the generation of artificially coloured contrast resembling conventional histological staining from label‐free SR‐µCT data and is ...
Sarah C. Irvine, Christian Lucas, Diana Krüger, Bianca C. Guedert, Julian Moosmann, Berit Zeller-Plumhoff   +5 more
wiley   +1 more source