Results 161 to 170 of about 1,766,278 (301)

MSpine: a prospective longitudinal study of spinal cord lesions in multiple sclerosis: MRI monitoring and prognostic factors for active disease. A study protocol. [PDF]

Neurol Res Pract
Bouweriks D, Kreiter D, Knippenberg SAM, Damoiseaux JGMC, Smolders J, van Eijk JJJ, Mommers EHH, de Beukelaar JWK, Olde Dubbelink TBG, Merry AHH, Hupperts RMM, Gerlach OHH.   +11 more
europepmc   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Focal intratesticular lesions including spontaneous hematomas in the acute scrotum: the pivotal role of ultrasound and MRI in diagnosis and management-a pictorial review. [PDF]

Insights Imaging
Rocher L, Hijazi M, Shaito F, Hani C, Bekdache O, Arama E, Zaag S.   +6 more
europepmc   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Point-of-care brain magnetic resonance imaging in children with head trauma (BRAINCHILD): Protocol for a prospective observational cohort study. [PDF]

PLoS One
Chaudhari PP, Guzman K, Toliao JM, Lozano S, Lee C, Shah P, Gonzalez F, De Souza BJ, Spurrier R, Chiarelli PA, Santoro JD, Durazo-Arvizu R, Doyle EK, Liu CJ, Nelson MD, Leporé N.   +15 more
europepmc   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Rotation matters: CT and MRI yield different tibiofemoral rotation angles in patellofemoral patients. An investigational plateau-anchored MRI method is descriptively associated with a smaller mean CT-MRI difference. [PDF]

J Exp Orthop
Anzillotti G, Tompkins MA, Agel J, Comfort SM, Arendt EA.   +4 more
europepmc   +1 more source

Towards a shuttle-based workflow for daily online magnetic resonance imaging-guided particle therapy: Anatomical robustness and organ variability in the female pelvis. [PDF]

Tech Innov Patient Support Radiat Oncol
Longarino FK, Droutsas D, Wessel L, Beyer C, Pestana R, Bauer J, Seidensaal K, Debus J, Klüter S, Arians N.   +9 more
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Utility of Diagnostic Arthroscopy Before Medial Patellofemoral Ligament Reconstruction in Pediatric and Adolescent Patients Without Articular Findings on Magnetic Resonance Imaging. [PDF]

Orthop J Sports Med
Archer H, Patterson K, Schwartzman JD, McKay SD, Kushare I.   +4 more
europepmc   +1 more source