Results 161 to 170 of about 18,476,439 (363)
Processing of 9E3 mRNA and regulation of its stability in normal and Rous sarcoma virus-transformed cells. [PDF]
, 1989 Mark Y. Stoeckle, Hidesaburô Hanafusa
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Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
Natural mRNA translation. I. General kinetic analysis of the process of one mRNA species translation [PDF]
, 1986 А. П. Потапов, A. V. El’skaya
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Alternative Splicing and Polyadenylation Contribute to the Generation of hERG1 C-terminal Isoforms
, 2010 The human ether-a-go-go-related gene 1 (hERG1) encodes the pore-forming subunit of the rapidly activating delayed rectifier potassium channel. Several hERG1 isoforms with different N- and C-terminal ends have been identified.
Gong, Qiuming +4 more
core
Comparative Study of Levels of Secondary Processing in Bulk mRNA from Dry and Germinating Wheat Embryos [PDF]
, 1981 B. G. Lane, Theresa D. TUMAITIS-KENNEDY
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Molecular Oncology, EarlyView.Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source
Cyclosporin A-binding protein (cyclophilin) of Neurospora crassa [PDF]
, 1988 Cyclophilin (cyclosporin A-binding protein) has a dual localization in the mitochondria and in the cytosol of Neurospora crassa. The two forms are encoded by a single gene which is transcribed into mRNAs having different lengths and 5' termini ...
Hartl, Franz-Ulrich +6 more
core
, 2015 Transcription initiation and mRNA maturation were long considered co-occurring but separately regulated events of gene control. In the past decade, gene promoters, the platforms of transcription initiation, have been assigned additional functions such as
Hilgers, V.
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trans-acting regulation of bovine leukemia virus mRNA processing [PDF]
, 1988 David Derse
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