Results 131 to 140 of about 199,785 (356)

New-onset giant cell arteritis following COVID-19 mRNA (BioNTech/Pfizer) vaccine: a double-edged sword? [PDF]

, 2022
A. M. Anzola Alfaro, Laura Trives-Folguera, Julia Martínez‐Barrio, Blanca Pinilla, José María Álvaro‐Gracia, J. Molina Collada   +5 more
openalex   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Polyvalent mpox mRNA vaccines elicit robust immune responses and confer potent protection against vaccinia virus

Cell Reports
Summary: The 2022 mpox outbreak led the World Health Organization (WHO) to declare it a public health emergency of international concern (PHEIC). There is a need to develop more effective and safer mpox virus (MPXV)-specific vaccines in response to the ...
Tianxi Ye, Jinge Zhou, Chen Guo, Kaiyue Zhang, Yuping Wang, Yanhui Liu, Junhui Zhou, Yalin Xie, Entao Li, Rui Gong, Jiancun Zhang, Xia Chuai, Sandra Chiu   +12 more
doaj   +1 more source

HAGE, a cancer/testis antigen expressed at the protein level in a variety of cancers [PDF]

, 2010
The search for novel tumour antigens that are either uniquely expressed or over-expressed in a wide variety of tumours is still ongoing. Because of their expression in a broad spectrum of cancers and limited expression in normal tissues, cancer/testis ...
Badoual, C, Linley, AJ, Mathieu, MG, McArdle, SEB, Reeder, SP, Rees, RC, Tartour, E   +6 more
core  

Translation elongation can control translation initiation on eukaryotic mRNAs [PDF]

, 2013
Synonymous codons encode the same amino acid, but differ in other biophysical properties. The evolutionary selection of codons whose properties are optimal for a cell generates the phenomenon of codon bias.
Aitken, Anand, Brachmann, Browne, Carlini, Chan, Charneski, Chu, Chu, Chu, Ciandrini, Dana, Firczuk, Fluitt, Gibson, Gould, Grant, Haar, Haar, Hense, Hershberg, Hu, Ikemura, Ingolia, Ingolia, Jeon, Kemp, Kotula, Kudla, Liti, Liu, Lombardi, McCarthy, Merritt, Mirzaei, Moriya, Mossadegh, Nagata, Neafsey, Outchkourov, Patel, Plant, Powell, Qian, Sala-Newby, Salas-Marco, Shalgi, Sikorski, Sinclair, Slimko, Stadler, Stark, Wolin, Yadava, Zhou, Zouridis   +55 more
core   +2 more sources

Unfolding and Degradation of Micellar Immunodrug Carriers Derived From End Group Modified Aliphatic Poly(Carbonate)s with Acid‐Responsive Ketal Side Groups

Advanced Materials, EarlyView.
An acid‐responsive polymeric micelle system based of aliphatic poly(carbonate)s with benzyl ketal side chains is designed for targeted immunodrug delivery. It can disassemble in endosomal environments, enabling site‐specific immunoactivation and enhanced biodegradability.
Adrian V. Hauck, Michael Fichter, Laura J. Rosenberger, Jannis Willig, Alexander Fuchs, Felicia Schön, Paul Schneider, Carolina Medina‐Montano, Taufiq Ahmad, Jessica Erlenbusch, Pol Besenius, Leonard Kaps, Matthias Bros, Stephan Grabbe, Volker Mailänder, Jürgen Groll, Lutz Nuhn   +16 more
wiley   +1 more source

Overlapping functionality of the Pht proteins in zinc homeostasis of streptococcus pneumoniae [PDF]

, 2014
Streptococcus pneumoniae is a globally significant pathogen that causes a range of diseases, including pneumonia, sepsis, meningitis, and otitis media. Its ability to cause disease depends upon the acquisition of nutrients from its environment, including
Eijkelkamp, Bart A., Harvey, Richard M., Hughes, Catherine E., McDevitt, Christopher A., Paton, James C., Plumptre, Charles D.   +5 more
core   +1 more source

Blunted humoral response after mRNA vaccine in patients with haematological malignancies [PDF]

, 2021
Mini Kamboj
openalex   +1 more source

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, EarlyView.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

Atypical Anti-Glomerular Basement Membrane Nephritis After the First Dose of the Severe Acute Respiratory Syndrome Coronavirus 2 mRNA Vaccine

, 2023
Shotaro Hoi, Masaya Ogawa, Chishio Munemura, Tomoaki Takata, Hajime Isomoto   +4 more
openalex   +2 more sources