Results 241 to 250 of about 199,785 (356)

Cellular immune response to the anti-SARS-CoV-2 BNT162b2 mRNA vaccine in pediatric autoimmune inflammatory rheumatic disease patients and controls [PDF]

Tali Eviatar, A Pappo, Tal Freund, Yishai Friedlander, Ori Elkayam, David Hagin, Merav Heshin‐Bekenstein   +6 more
openalex   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Computational design of an mRNA vaccine targeting antifungal-resistant Lomentospora prolificans. [PDF]

Sci Rep
Rehmani MBI, Arshad F, Khan MU, Ejaz H, Nishan U, Alotaibi A, Ullah R, Chen K, Ojha SC, Shah M.   +9 more
europepmc   +1 more source

Three Doses of Sars-Cov-2 Mrna Vaccine in Older Adults Result in Similar Antibody Responses But Reduced Cellular Cytokine Responses Relative to Younger Adults

Geir Bredholt, Marianne Sævik, Hanne Søyland, Thor Ueland, Fan Zhou, Rishi D. Pathirana, Anders Madsen, Juha Vahokoski, Sarah Lartey Jalloh, Bente Halvorsen, Tuva B. Dahl, Mai Chi Trieu, Kristin Greve-Isdahl Mohn, Karl A. Brokstad, Pål Aukrust, Camilla Tøndel, Nina Langeland, Bjørn Blomberg, Rebecaa Cox   +18 more
openalex   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

A BCMA-mRNA vaccine is a promising therapeutic for multiple myeloma.

Blood
Dutta D, Liu J, Wen K, Ray A, Salatino A, Liu X, Gulla A, Hideshima T, Song Y, Anderson KC.   +9 more
europepmc   +1 more source

Immuno-functionomics reveals geographical variation and a role for TLR8 in mRNA vaccine responses. [PDF]

iScience
Huisman W, Azimi S, Nguyen YN, de Kroon AC, de Ruiter K, Tahapary DL, Manurung MD, Pothast CR, Kruize YCM, Heemskerk MHM, Supali T, Visser LG, Roukens AHE, Yazdanbakhsh M, Jochems SP.   +14 more
europepmc   +1 more source

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses [PDF]

, 2018
Norbert Pardi, Michael J. Hogan, Martin S. Naradikian, Kaela Parkhouse, Derek W. Cain, Letitia D. Jones, M. Anthony Moody, Hans Verkerke, Arpita Myles, Elinor Willis, Celia C. LaBranche, David C. Montefiori, Jenna L Lobby, Kevin O. Saunders, Hua‐Xin Liao, Bette Korber, Laura L. Sutherland, Richard M. Scearce, Peter Hraber, István Tombácz, Hiromi Muramatsu, Houping Ni, Daniel A. Balikov, Zhongxia Li, Barbara L. Mui, Ying K. Tam, Florian Krammer, Katalin Karikó, Patricia Polacino, Laurence C. Eisenlohr, Thomas D. Madden, Michael J. Hope, Mark G. Lewis, Kelly K. Lee, Shiu‐Lok Hu, Scott E. Hensley, Michael P. Cancro, Barton F. Haynes, Drew Weissman   +38 more
openalex   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

High levels of nonblocking anti-interferon and anticytokine autoantibodies in individuals with mRNA vaccine-induced systemic allergic reactions. [PDF]

J Allergy Clin Immunol Glob
Kalaycioglu M, Feng A, Dhingra S, Khalid MB, Nadeau KC, Utz PJ, Frischmeyer-Guerrerio PA.   +6 more
europepmc   +1 more source