Results 11 to 20 of about 113,396 (305)

Mrp Antiporters Have Important Roles in Diverse Bacteria and Archaea

Frontiers in Microbiology, 2017
Mrp (Multiple resistance and pH) antiporter was identified as a gene complementing an alkaline-sensitive mutant strain of alkaliphilic Bacillus halodurans C-125 in 1990.
Masahiro Ito, Masahiro Ito, Masato Morino, Masato Morino, Terry A. Krulwich   +4 more
doaj   +2 more sources

RNase MRP and disease

WIREs RNA, 2010
AbstractThe human RNase MRP complex consists of a catalytic RNA and several protein components. RNase MRP is a ubiquitously expressed eukaryotic endoribonuclease that cleaves various RNAs, including ribosomal, messenger, and mitochondrial RNAs, in a highly specific fashion.
Mattijssen, S., Welting, T.J.M., Pruijn, G.J.M., Pruijn, G.J.M.   +3 more
openaire   +4 more sources

Folic acid (FA)-conjugated mesoporous silica nanoparticles combined with MRP-1 siRNA improves the suppressive effects of myricetin on non-small cell lung cancer (NSCLC).

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020
Non-small cell lung cancer (NSCLC) is a common diagnosed cancer disease worldwide and its management remains a challenge. Synergistic cancer therapeutic strategy is interesting for multiple advantages, such as excellent targeting accuracy, low side ...
Yinxue Song, Bin Zhou, Xiangyang Du, Yong Wang, Jie Zhang, Yanqiu Ai, Zongjiang Xia, Gaofeng Zhao   +7 more
semanticscholar   +1 more source

Structural insight into precursor ribosomal RNA processing by ribonuclease MRP

Science, 2020
Adapted to the task at hand RNA-based catalysts perform fundamental tasks in cellular RNA metabolism, especially in eukaryotes, where RNAs are cut by specialized ribonucleoproteins (RNPs) as part of ribosome assembly or messenger RNA regulation or ...
P. Lan, Bin Zhou, M. Tan, Shaobai Li, Mi Cao, Jian Wu, M. Lei   +6 more
semanticscholar   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

Hepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu, Ya Wang, Mina Khoshdeli, Matt Peach, Jen‐Chieh Chuang, Julie Lin, Wen‐Wei Tsai, Sangeetha Mahadevan, Wesley Minto, Lauri Diehl, Ruchi Gupta, Michael Trauner, Keyur Patel, Mazen Noureddin, Kris V. Kowdley, Aliya Gulamhusein, Christopher L. Bowlus, Ryan S. Huss, Robert P. Myers, Chuhan Chung, Andrew N. Billin   +20 more
wiley   +1 more source

Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP

Nature Communications, 2020
RNase MRP is an essential eukaryotic ribonucleoprotein complex involved in the maturation of rRNA and the regulation of the cell cycle. RNase MRP is related to the ribozyme-based RNase P, but it has evolved to have distinct cellular roles.
A. Perederina, Di Li, Hyunwook Lee, C. Bator, I. Berezin, S. Hafenstein, A. S. Krasilnikov   +6 more
semanticscholar   +1 more source

Marine Biodiversity of Coral Reef Fishes in Pieh Marine Recreational Park After Bleaching and Acanthaster Outbreaks

Jurnal Ilmiah Perikanan dan Kelautan, 2022
Highlight Research • After bleaching disturbance and Acanthaster planci outbreaks, herbivore fishes species were dominated in MRP Pieh • This explains the marine recreational activities in utilization zone MRP Pieh have no impact on reducing fish ...
Risandi Dwirama Putra, Muhammad Abrar, Rikoh Manogar Siringoringo, Ni Wayan Purnamsari, Pradipta Agustina, MD Jayedul Islam   +5 more
doaj   +1 more source

Dihydroartemisinin ameliorates innate inflammatory response induced by Streptococcus suis-derived muramidase-released protein via inactivation of TLR4-dependent NF-κB signaling

Journal of Pharmaceutical Analysis, 2023
Muramidase-released protein (MRP) is now being recognized as a critical indicator of the virulence and pathogenicity of Streptococcus suis (S. suis). However, the identification of viable therapeutics for S.
Yun Ji, Kaiji Sun, Ying Yang, Zhenlong Wu   +3 more
doaj   +1 more source

Non-Coding RNA Sequencing of Equine Endometrium During Maternal Recognition of Pregnancy. [PDF]

, 2019
Maternal recognition of pregnancy (MRP) in the mare is not well defined. In a non-pregnant mare, prostaglandin F2α (PGF) is released on day 14 post-ovulation (PO) to cause luteal regression, resulting in loss of progesterone production. Equine MRP occurs
Bouma, Gerrit J, Bruemmer, Jason E, Cameron, Ashley D, Canovas, Angela, Coleman, Stephen J, Hess, Ann M, Islas-Trejo, Alma D, Kalbfleisch, Ted, Klohonatz, Kristin M, Medrano, Juan F, Reed, Kailee J   +10 more
core   +1 more source

Impact of JNK and Its Substrates on Dendritic Spine Morphology

Cells, 2020
The protein kinase JNK1 exhibits high activity in the developing brain, where it regulates dendrite morphology through the phosphorylation of cytoskeletal regulatory proteins.
Emilia Komulainen, Artemis Varidaki, Natalia Kulesskaya, Hasan Mohammad, Christel Sourander, Heikki Rauvala, Eleanor T. Coffey   +6 more
doaj   +1 more source