Results 191 to 200 of about 33,160 (297)

Impact of FCGR2A and FCGR3A Gene Variants on the Response to Rituximab in Patients With Glomerular Diseases

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Rituximab is an anti‐CD20 monoclonal antibody used in autoimmune diseases, including glomerular diseases. The FCGR2A (rs1801274) and FCGR3A (rs396991) variants have been suggested to affect rituximab efficacy; this study evaluates their impact on rituximab efficacy in glomerular diseases.
María Larrosa‐García, Irene Agraz Pamplona, Susana Rojo Tolosa, Alberto Jiménez Morales, María Teresa Sanz Martínez, Mónica Martínez Gallo, Roger Colobran, Helena Genestal Vicente, Nerea Moreno Pena, Roxana Paola Bury Macías, José Bruno Montoro Ronsano   +10 more
wiley   +1 more source

Luteinizing hormone activates the Hippo pathway to promote progesterone synthesis in bovine luteal cells. [PDF]

Cell Commun Signal
Tamanaeifar F, Owolabi BA, Monaco CF, Moses RM, Castillo AC, Cupp AS, Davis JS, Plewes MR.   +7 more
europepmc   +1 more source

AEG‐AESPANC‐OPGE‐SIED‐SPG Ibero‐Latin American Guidelines on Acute Pancreatitis (iLATAM‐AP)

United European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Introduction Acute pancreatitis (AP) is a major cause of gastrointestinal hospitalizations worldwide. Although typically self‐limiting, up to one‐third of cases develop complications associated with increased morbidity and mortality. Despite recent advances that have improved outcomes, clinical heterogeneity necessitates updated, evidence ...
Karina Cárdenas‐Jaén, Lucía Guilabert, Emma Martínez‐Moneo, Carla Mancilla, Miguel Bispo, Pedro Moutinho‐Ribeiro, Rodrigo Mansilla, Andreia Rei, Ana García García de Paredes, Antonio López‐Serrano, Bruno Rosa, Claudia Sánchez‐Marín, Daniel de la Iglesia, Edson Guzmán‐Calderon, Eduardo Rodrigues‐Pinto, Eva Marín‐Serrano, Fabio Ausania, Fauze Maluf‐Filho, Guido Villagómez, Humberto Cristino, Isabel Pascual‐Moreno, José A. Gonzalez, José M. Ramia, João Lopes‐Delgado, Lucas Granero, Mario Peláez‐Luna, María Francisco, Natalia Corzo‐Zamora, Ricardo Rio‐Tinto, Rómulo D. Vargas, Sandra Basso, Susana Lopes, Susana Marques, William Manzanares, Zoltán Berger, Irene Carrillo, José Joaquín Mira‐Solves, Alberto Espino, Adriana Cowdin, Alejandro Piscoya, Alexandra Fernandes, Noelia Rodríguez‐Ferreiro, Neftalí Jara Pérez‐López, Beatriz Valero, Enrique de‐Madaria   +44 more
wiley   +1 more source

Fermented Soy Protein Maillard Product Prevents Bone Loss via TNF-α Suppression and Gut-Bone Axis Modulation in Ovariectomized Mice. [PDF]

J Microbiol Biotechnol
Bae HJ, Joung JY, Choi HS, Han JS, Kim JH, Kim JK, Oh NS.   +6 more
europepmc   +1 more source

Assessing Intraurban Variation in Heat‐Attributable Health Burden to Inform Local Interventions

GeoHealth, Volume 10, Issue 6, June 2026.
Abstract Extreme heat exposure leads to excess cardiovascular morbidity and mortality among older adults, but misalignment in the geographic scales of health data and intraurban heat exposure make it challenging to inform local interventions. We introduce an adaptable framework for developing health burden estimates at finer geographic scales by ...
K. Burley Farr, E. M. McInroe, W. L. Tsai, A. Hsu, A. G. Rappold   +4 more
wiley   +1 more source

Evaluation of Potentially Inappropriate Medications Prescribed to Older Adults Upon Emergency Department Discharge. [PDF]

Acad Emerg Med
Schowe J, North AM, Schuchter K, Hunold KM, Rozycki E.   +4 more
europepmc   +1 more source

Loss of Brain‐Derived Estrogen Is Associated With Sex‐ and Age‐Dependent Alterations in Memory, Affective Behavior, and Hippocampal Extracellular Matrix Gene Expression

Aging Cell, Volume 25, Issue 6, June 2026.
Age, sex, and estrogen loss are widely recognized risk factors for Alzheimer's disease. Here, we show that brain‐specific aromatase knockout (bArKO) and the resulting estrogen loss lead to memory impairment, reduced social interaction, and extracellular environment dysregulation selectively in aged female mice, but not in young female or male mice ...
Natalie C. Piehl, Ariel W. Halle, Guadalupe Rodriguez, Andrea Locci, Stacy Kujawa, Caroline Haywood, John Coon V, Ross P. McNally, Zaina A. Karim, Tianming You, Hongxin Dong, Serdar E. Bulun, Hong Zhao   +12 more
wiley   +1 more source

Effectiveness of motor relearning program in sit-to-stand transfer and activities of daily living among chronic stroke patients - a prospective, multicenter, randomized controlled trial. [PDF]

J Comp Eff Res
Alfaleh KA, Shaik AR, Balasubramanian K, Alshehri MM, Sanjeevi RR, Esht V, Alsalem WO, Shahhar AM, Alothman SA.   +8 more
europepmc   +1 more source

Disordered Bile Acid Metabolism in Alcohol‐Related Hepatitis

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 12, Page 1658-1672, June 2026.
Serum conjugated primary bile acids accumulate in alcohol‐related hepatitis due to downregulation of hepatocyte bile acid transporters. Hepatocyte growth factor is elevated in alcohol‐related hepatitis and downregulates BSEP expression. This detrimentally affects the hepatoprotective adaptive reduction in NTCP/increase in BSEP seen in cholestasis ...
Luke D. Tyson, Stephen Atkinson, Benjamin H. Mullish, Alexandros Pechlivanis, Michael Allison, Andrew Austin, Katie Chappell, Stuart J. Forbes, Ewan H. Forrest, Alastair M. Kilpatrick, Tong Liu, Laura Martinez‐Gili, Steven Masson, Mark J. W. McPhail, Joao Nunes, Paul Richardson, Daniel Rodrigo‐Torres, Stephen D. Ryder, Mark Wright, Vishal C. Patel, Nikhil Vergis, Elaine Holmes, Mark R. Thursz   +22 more
wiley   +1 more source

Beyond the <i>emm</i>-type: fine-tuning Group A <i>Streptococcus</i> typing with Enn and Mrp. [PDF]

Microbiol Spectr
Widomski C, Bruyns C, Schiavolin L, de Crombrugghe G, Smeesters PR, Botteaux A.   +5 more
europepmc   +1 more source