Haemophilia, Volume 28, Issue 6, Page 1022-1032, November 2022., 2022 Abstract Introduction Congenital afibrinogenaemia and hypofibrinogenaemia are rare coagulation disorders where clotting is impaired due to a lack of fibrinogen. Consequent bleeding episodes (BEs) are treated using human fibrinogen concentrate (HFC). Aim This post‐hoc analysis compared HFC pharmacokinetics (PK) and dosing between patient age groups and ...
Claudia Djambas Khayat +6 more
wiley +1 more source
Pharmacology, safety, efficacy and clinical uses of the COX‐2 inhibitor robenacoxib
Journal of Veterinary Pharmacology and Therapeutics, Volume 45, Issue 4, Page 325-351, July 2022., 2022 Abstract Robenacoxib is a veterinary‐approved non‐steroidal anti‐inflammatory drug (NSAID) of the coxib group. It possesses anti‐hyperalgesic, anti‐inflammatory and anti‐pyretic properties. Robenacoxib inhibits the cyclooxygenase (COX)‐2 isoform of COX selectively (in vitro IC50 ratios COX‐1:COX‐2, 129:1 in dogs, 32:1 in cats). At registered dosages (2
Peter Lees +5 more
wiley +1 more source
Discrete Dynamics in Nature and Society, Volume 2021, Issue 1, 2021., 2021 The rent of farmland transfer represents the economic realization of farmland contracts and management rights of agricultural households. A three‐stage dynamic game model with three players is constructed in this paper to study the mechanism causing an increase in farmland transfer rent.
Hong Li, Xian Zhang, Daqing Gong
wiley +1 more source
Research on the Modification Plan of HVDC Transfer Switch Arrester
南方能源建设, 2022 [Introduction] During the earth return and metallic return mode conversion of China's HVDC transmission projects in operation, several MRTB (metallic return transfer breaker) or ERTB (earth return transfer breaker) oscillation platform arrester damage ...
LU Yuxin +5 more
doaj +1 more source
Brazilian Journal of Infectious Diseases, 2022 D.W.D, 39 anos, masculino, branco, diagnóstico recente de infecção tardia por HIV, CD4 de 216 cel/mm (9,95%) e carga viral 4.667 cópias/ml, interna no Hospital Nossa Senhora de Conceição para elucidação de febre persistente há 3 meses, linfodomegalias ...
Igor de Souza Bernardotti +6 more
doaj +1 more source
Modified reservoir quality indicator methodology for improved hydraulic flow unit characterization using the normalized pore throat methodology (Niger Delta field as case study) [PDF]
, 2016 The detailed characterization of complex reservoir units, typical of the thin-bedded canyon turbidites system within the clastic environment is essential for accurate reservoir modelling.
David, O. Ogbe +2 more
core +2 more sources
Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome [PDF]
, 2014 Rett syndrome (RTT) is a severe X-linked neurodevelopmental disorder mainly affecting females and is associated with mutations in MECP2, the gene encoding methyl CpG-binding protein 2.
Alexander, Mark Edward +21 more
core +1 more source
Tuberculosis course in a patient with Fahr’s disease (a clinical case report)
Zaporožskij Medicinskij Žurnal, 2018 In the present context, pulmonary tuberculosis, especially its resistant forms, is an urgent problem of society, not only inUkraine, but also throughout the world.
O. M. Raznatovska +3 more
doaj +1 more source
Can Ptilinopus greyii (Columbidae) Disperse Seeds in New Caledonia’s Dry Forests? [PDF]
, 2010 v. ill. 23 cm.QuarterlyConservation of endangered habitats of South Pacific islands is partially dependent on activity of seed dispersers. In consuming fruits, animals can spread seeds from parent plants to distant sites, thus contributing to plant ...
Barre, Nicolas +2 more
core +4 more sources
Altered tissue degradation and distribution of Atrial Natriuretic Peptide in patients with idiopathic dilated cardiomyopathy and its relationship with clinical severity of the disease and sodium handling [PDF]
, 1995 Background Atrial natriuretic peptide (ANP) has been suggested to play an important role in heart failure, preserving cardiorenal homeostasis through maintenance of the sodium balance and inhibition of the detrimental effects of ...
A. Biagini +6 more
core +1 more source