Results 91 to 100 of about 3,344,514 (294)

داستان كيوك (MS 195); داستان كسك باش (MS 196); داستان وفات فاطمة الزهرا (MS 197); داستان ابراهيم (MS 198); داستان حقايق (MS 199); مولود النبى (MS 200); علم حال (MS 201)

open access: yes
Birbirinden farklı 7 adet yazmanın bir araya getirilmesiyle oluşturulmuş ve ciltlenmiş bir eserdir (Yazma numaraları : MS 195, MS 196, MS 197, MS 198, MS 199, MS 200, MS 201).
Sadreddin / صدر الدين (MS 195); Kirdeci Ali / كيردجى على (MS 196); Süleyman Çelebi [d. 825 / 1422] / سليمان چلبى (MS 200); Unidentified (MS 197, MS 198, MS 199, MS 201)
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

خوباننامه (MS 174); زنان نامه (MS 175); رقاص نامه (MS 176)

open access: yes
Bu cilt, birbirinden farklı 3 yazmanın bir araya getirilmesiyle oluşturulmuştur (Yazma numaraları : MS 174, MS 175, MS 176). Üç eser de Osmanlıca yazılmıştır. MS 174, 1792 yılına tarihlenirken, diğer iki yazmanın kaleme alınma tarihi bilinmemektedir.
Enderunlu Fazıl [d. 1225 / 1810] / فاضل اندرونى (MS 174, MS 175, MS 176)
core  

Chemical Analysis of Pesticides Using GC/MS, GC/MS/MS, and LC/MS/MS

open access: yes, 2011
There are well over 500 registered pesticides worldwide for use in agricultural regions and new agrochemicals are introduced to the marketplace continuously. This chapter deals with the chemical analysis methods for the main pesticide chemical classes that are most frequently analyzed with gas chromatography (GC) or liquid chromatography (LC) coupled ...
openaire   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

ديوان كانى (MS 384); منشأت (MS 385)

open access: yes
Birbirinden farklı 2 adet yazmanın bir araya getirilmesiyle oluşturulmuş ve ciltlenmiş bir eserdir (Yazma numaraları : MS 384, MS 385). Her iki yazma da Osmanlıca olup 1797 yılında yazılmıştır.
Kāni Ebūbekir b. Abdullāh Tokatlı [d. 1206 / 1792] / كانى ابوبكر (MS 384, MS 385)
core  

Two-dimensional LC-MS/MS to enhance ceramide and phosphatidylcholine species profiling in mouse liver

open access: yes, 2017
A two-dimensional (2D) hydrophilic interaction liquid chromatography (HILIC) and reverse-phase (RP) liquid chromatography (LC) system coupled with triple-quadrupole mass spectrometry (MS) was developed to comprehensively profile ceramides and ...
郭明良;吳焜裕;林靖愉   +1 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

سرکذشت (MS 52); مبداء و معاد (MS 53); هدية المشتاق فى شرح مسلک العشاق (MS 54)

open access: yes
Birbirinden farklı 3 adet yazmanın bir araya getirilmesiyle oluşturulmuş ve ciltlenmiş bir eserdir (Yazma numaraları : MS 52, MS 53, MS 54). MS 52 : “Tarîkat-i aliye-i Bayramiyyeden taife-i Melâmiyyenin anane ve iradetleri ve keyfiyet-i sohbetleri ve aşk
La'lì-zāde Abdü’l-bākì [d. 1159 / 1746] / لعلی زاده عبد الباقی (MS 52, MS 53, MS 54)
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy