British Journal of Clinical Pharmacology, EarlyView.Background Long‐acting intramuscular cabotegravir plus rilpivirine (LA‐CAB + RPV) is an effective maintenance antiretroviral regimen for virologically suppressed people with HIV. However, its use in individuals receiving chronic anticoagulation is limited by concerns regarding intramuscular bleeding risk, and real‐world data are scarce.
Montserrat Laguno +13 more
wiley +1 more source
Musculoskeletal Disorders in Dentists: A Practical Review and Self-Management Framework. [PDF]
Int Dent JMaksym V.
europepmc +1 more source
Plasma and breast milk pharmacokinetics of suvorexant in healthy lactating women
British Journal of Clinical Pharmacology, EarlyView.Aim This paper aims to evaluate the plasma and breast milk pharmacokinetics of suvorexant, an orexin receptor antagonist used to treat insomnia at a maximum dose of 20 mg, in healthy lactating women. Methods The paper reports on an open‐label Phase 1 study in 12 healthy lactating women.
Jacqueline McCrea +10 more
wiley +1 more source
Smoking-attributable burden of musculoskeletal disorders, 1990-2021, with exploratory projections to 2050: A secondary dataset analysis of the Global Burden of Disease Study 2021. [PDF]
Tob Induc DisFu Z, Zhang Y, Chen Z.
europepmc +1 more source
Acute toxic leucoencephalopathy following protonitazene ingestion
British Journal of Clinical Pharmacology, EarlyView.Background Distribution of illicit counterfeit alprazolam containing the highly potent synthetic opioid‐receptor agonist protonitazene recently resulted in a number of severe overdoses in Ireland. We report three cases that presented to our hospital, within 6 weeks of one another, following ingestion of illicitly‐sourced alprazolam.
Ruadhan O'Laoi +5 more
wiley +1 more source
Integrative risk mapping of musculoskeletal disorders among office workers: a hybrid Delphi-Fuzzy AHP approach. [PDF]
BMC Musculoskelet DisordAbbasinia M, Entezarizarch E.
europepmc +1 more source
BMEMat, EarlyView.A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue +4 more
wiley +1 more source
RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging
Biological Reviews, EarlyView.ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad +5 more
wiley +1 more source
World Trade Center related acute traumatic injuries and musculoskeletal disorders: Clinical best practices. [PDF]
Arch Environ Occup HealthPrampero MZ, Shaw RL, Calvert GM.
europepmc +1 more source
Business Strategy and the Environment, EarlyView.ABSTRACT Given the critical role that banks play in sustainable development through their financial intermediation and capital allocation functions, assessing their sustainability performance has become an increasingly important research issue.
Özcan Işık +3 more
wiley +1 more source